Research

Research ›› 2025, Vol. 8 ›› Issue (11) : 1027 - . DOI: 10.34133/research.1027

Review Article

Scaffold-Mediated Microenvironmental Modulation Targeting Osteoclasts for ONFH Niche Reprogramming

Hongyu Quan ¹^,²^,³ ,
Yuwei He ⁴ ,
Pengcheng Xiao ¹^,²^,³ ,
Zhenglin Zhu ¹^,²^,³ ,
Xiuteng Zhou ⁵^,^* ,
Zhong Alan Li ⁶^,⁷^,^* ,
Yiting Lei ¹^,²^,³^,⁶^,^* ,
Hong Jiang ⁴^,^* ,
Wei Huang ¹^,²^,³^,^*

Author information +

¹Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.

²Chongqing Municipal Health Commission Key Laboratory of Musculoskeletal Regeneration and Translational Medicine, Chongqing 400016, China.

³Orthopaedic Research Laboratory of Chongqing Medical University, Chongqing 400016, China.

⁴Department of Biomedical Materials Science, College of Biomedical Engineering, Army Medical University (Third Military Medical University), Chongqing 400038, China.

⁵National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences/State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Beijing 100700, China.

⁶Department of Biomedical Engineering, The Chinese University of Hong Kong, NT, Hong Kong SAR 999077, China.

⁷Key Laboratory of Regenerative Medicine, Ministry of Education, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.

^* Address correspondence to: zxt_0508@163.com (X.Z.);

alanli@cuhk.edu.hk (Z.A.L.);

leiyit614@163.com (Y.L.);

jh@tmmu.edu.cn (H.J.);

huangwei68@263.net (W.H.)

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Received	Accepted	Published
2025-10-29	2025-11-16
Issue Date
2026-11-01

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