Research

Research ›› 2026, Vol. 9 ›› Issue (5) : 1303 - . DOI: 10.34133/research.1303

RESEARCH ARTICLE

Lumi-Guide: An Artificial-Intelligence-Driven Multimodal Framework for Optimizing Personalized Neoadjuvant Therapy Decision-Making in Luminal Breast Cancer

Yanting Liang ¹^,² ,
Xiaobo Chen ¹^,²^,³ ,
Penghao Lai ¹^,² ,
Shaoxuan Huang ¹^,²^,³ ,
Minping Hong ⁴ ,
Wenjing Jiang ¹^,² ,
Hongjie Cai ²^,⁵ ,
Yujie Ying ¹^,² ,
Kexin Chen ¹^,² ,
Kaiqi Hou ¹^,²^,³ ,
Yiying Li ⁶ ,
Zhitao Wei ¹^,² ,
Chinting Wong ¹^,² ,
Fan Yang ¹^,²^,³ ,
Yuelong Yang ¹^,² ,
Jie Hou ⁷ ,
Zaiyi Liu ¹^,² ,
Xin Chen ²^,⁸^,^* ,
Ying Wang ⁹^,^* ,
Changhong Liang ¹^,²^,^* ,
Zhenwei Shi ¹^,²^,^*

Author information +

¹Department of Radiology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, China.

²Guangdong Provincial Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application, Guangzhou 510080, China.

³Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.

⁴Department of Radiology, Zhejiang Chinese Medical University Affiliated Jiaxing TCM Hospital, Jiaxing 314033, China.

⁵The Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.

⁶Department of Breast Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

⁷Cancer Center, Department of Radiology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou 310014, China.

⁸Department of Radiology, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, China.

⁹Department of Medical Ultrasonics, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China.

^* Address correspondence to: eyxinchen@scut.edu.cn (X.C.);

^* Address correspondence to: liuivy527@163.com (Y.W.);

^* Address correspondence to: liangchanghong@gdph.org.cn (C.L.);

^* Address correspondence to: shizhenwei@gdph.org.cn (Z.S.)

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Received	Accepted	Published
2025-11-20	2026-05-11
Issue Date
2026-10-16

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