Research

Research ›› 2026, Vol. 9 ›› Issue (5) : 1266 - . DOI: 10.34133/research.1266

RESEARCH ARTICLE

Neuromodulation and Copper Chelation Reverse Sleep Fragmentation-Aggravated Myocardial Ischemia–Reperfusion Injury by Targeting NET-Induced Endothelial Cuproptosis

Pilong Shi ¹^,²^,³ ,
Yuetong Sha ¹^,³ ,
Xue Guan ⁴ ,
Jiawei Wu ⁵ ,
Jing Yang ¹ ,
Dongyu Min ² ,
Cong Wang ⁶ ,
Yonggang Cao ¹ ,
Xinran Wang ¹ ,
Yuandong Qiao ⁵^,⁷^,⁸^,^* ,
Hongli Sun ¹^,³^,^*

Author information +

¹Department of Pharmacology, Harbin Medical University, Heilongjiang 163319, China.

²Experimental Center of Traditional Chinese Medicine, the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Liaoning 110000, China.

³Key Laboratory of Basic Research and Health Management on Chronic Diseases in Heilongjiang Province, Harbin Medical University, Heilongjiang 163319, China.

⁴Department of Medical Morphology, Harbin Medical University, Heilongjiang 163319, China.

⁵Key Laboratory of Frigid Zone Exercise Health Research and Translation in Heilongjiang Province, Harbin Medical University, Heilongjiang 163319, China.

⁶Department of Cardiology, Daqing People’s Hospital, Heilongjiang 163319, China.

⁷Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Heilongjiang 150081, China.

⁸Department of Medical Genetics, Harbin Medical University, Heilongjiang 150081, China.

^* Address correspondence to: qiaoyuandong@hrbmu.edu.cn (Y.Q.);

^* Address correspondence to: sunhongli@hmudq.edu.cn (H.S.)

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Received	Accepted	Published
2026-02-09	2026-04-02
Issue Date
2026-10-16

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