¹Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai 200025, PR China.

²Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Turku 20520, Finland.

³Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou 215000, China.

⁴State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, China.

⁵Institute of Biomedicine, University of Turku, Turku 20014, Finland.

⁶Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku 20520, Finland.