Research

Research ›› 2026, Vol. 9 ›› Issue (9) : 1424 - . DOI: 10.34133/research.1424

RESEARCH ARTICLE

Longitudinal Characterization of Giant ANK2-Depleted Monkeys Suggests Neurodevelopmental-Disorder-Like Phenotypes

Hong-Di Huang ¹^,²^,³ ,
Yun-Chao Ji ² ,
Long Zhang ¹^,²^,³ ,
Min Xu ¹^,²^,³ ,
Yicheng Qiao ⁴^,⁵ ,
Chen-Yao Li ¹^,²^,³ ,
Hui-Hen Xie ² ,
Yu Li ¹^,² ,
Bao-Lin Zhang ¹^,²^,⁶ ,
Ming-Hao Qiu ² ,
Ya-Li Zhang ¹^,²^,³ ,
Xiao-Mei Yu ¹^,² ,
Yun-Bing Zhang ² ,
Yun Wang ² ,
Qiong Wang ² ,
Yi-Jiang Li ² ,
Long-Bao Lv ¹^,²^,³ ,
Xing-Xu Huang ⁷ ,
Bing-Yu Mao ¹^,²^,³^,⁸ ,
Dong-Dong Wu ¹^,²^,³^,⁸ ,
Ping Zheng ¹^,²^,³^,⁸^,^* ,
Ning Liu ⁴^,⁵^,^* ,
Jian-Hong Wang ¹^,²^,³^,^* ,
Yong-Gang Yao ¹^,²^,³^,⁸^,^*

Author information +

¹State Key Laboratory of Genetic Evolution and Animal Models, Yunnan Key Laboratory of Animal Models and Human Disease Mechanisms, and Yunnan Engineering Center on Brain Disease Models, Kunming, Yunnan 650204, China.

²National Research Facility for Phenotypic & Genetic Analysis of Model Animals (Primate Facility) and National Resource Center for Non-Human Primates, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650107, China.

³Kunming College of Life Sciences, University of Chinese Academy of Sciences, Kunming, Yunnan 650204, China.

⁴State Key Laboratory of Cognitive Science and Mental Health, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.

⁵College of Life Sciences, University of Chinese Academy of Sciences, Beijing 101408, China.

⁶Yunnan Key Laboratory of Biodiversity Information, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650201, China.

⁷School of Life Science and Technology, Shanghai Tech University, Shanghai, China.

⁸KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650204, China.

^* Address correspondence to: zhengp@mail.kiz.ac.cn (P.Z.);

^* Address correspondence to: liuning@ibp.ac.cn (N.L.);

^* Address correspondence to: wangjh@mail.kiz.ac.cn (J.-H.W.);

^* Address correspondence to: yaoyg@mail.kiz.ac.cn (Y.-G.Y.)

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Received	Accepted	Published
2026-02-08	2026-08-16
Issue Date
2026-10-16

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