Research

Research ›› 2026, Vol. 9 ›› Issue (3) : 1044 - . DOI: 10.34133/research.1044

RESEARCH ARTICLE

Inhibition of DDX5-Mediated G-Quadruplex Unwinding in the β-Catenin 5′-UTR by Magnesium Isoglycyrrhizinate Alleviates Chemotherapy-Induced Intestinal Injury

Ying Zhang ¹^,² ,
Wenqiang Fu ³ ,
Yaohui Wang ² ,
Anyuan Wu ¹^,⁴ ,
Zhenzhen Zhu ¹^,⁴ ,
Xunkai Yin ¹^,⁴ ,
Yan Li ⁵ ,
Yongdi Sun ¹^,⁴ ,
Wenpu Shi ⁶ ,
Jianming Cheng ¹^,^* ,
Lihong Hu ¹^,⁴^,⁷^,^* ,
Jian Liu ¹^,⁴^,^* ,
Jian Cui ¹^,⁴^,^*

Author information +

¹School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.

²Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, China.

³High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei 230031, China.

⁴Jiangsu Key Laboratory for Functional Substance of Chinese Medicine, Stake Key Laboratory Cultivation Base for TCM Quality and Efficacy, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.

⁵State Key Laboratory of Pharmaceutical Biotechnology, School of Life Science, Nanjing University, Nanjing 210023, China.

⁶The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang 712000, China.

⁷China Joint Graduate School of Traditional Chinese Medicine, Suzhou 215105, China.

^* Address correspondence to: 320320@njucm.edu.cn (J. Cheng);

^* Address correspondence to: lhhu@njucm.edu.cn (L.H.);

^* Address correspondence to: liujian623@njucm.edu.cn (J.L.);

^* Address correspondence to: cuijian@njucm.edu.cn (J. Cui)

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Received	Accepted	Published
2025-08-26	2025-12-01
Issue Date
2026-10-16

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