Research

Research ›› 2024, Vol. 7 ›› Issue (3) : 0346 . DOI: 10.34133/research.0346

Research Article

B Cells and IL-21-Producing Follicular Helper T Cells Cooperate to Determine the Dynamic Alterations of Premetastatic Tumor Draining Lymph Nodes of Breast Cancer

Xinrui Mao ¹^,²^,^† ,
Xinyu Tang ¹^,²^,^† ,
Hong Pan ¹^,²^,^† ,
Muxin Yu ¹^,²^,^† ,
Sihan Ji ¹^,² ,
Wen Qiu ³ ,
Nan Che ⁴ ,
Kai Zhang ²^,⁵^,⁶ ,
Zhendong Huang ²^,⁷ ,
Yunshan Jiang ¹^,² ,
Ji Wang ¹^,² ,
Zhaoyun Zhong ¹^,² ,
Jiaming Wang ¹^,² ,
Mingduo Liu ¹^,² ,
Mingkang Chen ²^,⁸ ,
Wenbin Zhou ¹^,²^,^* ,
Shui Wang ¹^,²^,^*

Author information +

¹Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China.

²Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center For Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing 211166, China.

³Department of Immunology, Nanjing Medical University, Nanjing 211166, China.

⁴Department of Rheumatology and Immunology, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China.

⁵Pancreatic Center & Department of General Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing 210029, Jiangsu, China.

⁶ Pancreas Institute of Nanjing Medical University, Nanjing 210029, Jiangsu, China.

⁷Department of Pathology, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China.

⁸Department of Ophthalmology, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China.

^* Address correspondence to: shwang@njmu.edu.cn (S.W.); zhouwenbin@njmu.edu.cn (W.Z.)

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Received	Accepted	Published
2023-12-04	2024-03-06
Issue Date
2025-07-24

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