Research

Research ›› 2024, Vol. 7 ›› Issue (1) : 0301 . DOI: 10.34133/research.0301

Research Article

Transferrin Is Up-Regulated by Microbes and Acts as a Negative Regulator of Immunity to Induce Intestinal Immunotolerance

Xiaopeng Tang ¹^,²^,^† ,
Mingqian Fang ¹^,^† ,
Ruomei Cheng ¹^,^† ,
Junkun Niu ³^,⁴^,^† ,
Xiaoshan Huang ¹^,⁵^,^† ,
Kuanhong Xu ⁶^,^† ,
Gan Wang ¹ ,
Yang Sun ³^,⁴ ,
Zhiyi Liao ¹^,⁵ ,
Zhiye Zhang ¹ ,
James Mwangi ¹^,⁵ ,
Qiumin Lu ¹ ,
Aili Wang ⁷ ,
Longbao Lv ¹ ,
Chao Liu ¹ ,
Yinglei Miao ³^,⁴^,^* ,
Ren Lai ¹^,^*^,^‡

Author information +

¹Engineering Laboratory of Peptides of Chinese Academy of Sciences, Key Laboratory of Bioactive Peptides of Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, National Resource Center for Non-Human Primates, National Research Facility for Phenotypic & Genetic Analysis of Model Animals (Primate Facility), and Sino-African Joint Research Center, New Cornerstone Science Institute, Kunming Institute of Zoology, the Chinese Academy of Sciences, No.17 Longxin Road, Kunming, Yunnan, 650201, China.

²School of Basic Medicine, Qingdao University, Qingdao 266071, Shandong, China.

³Department of Gastroenterology, First Affiliated Hospital of Kunming Medical University, Yunnan Institute of Digestive Disease, Kunming 650032, Yunnan, China.

⁴ Yunnan Province Clinical Research Center for Digestive Diseases, Kunming 650032, Yunnan, China.

⁵Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming 650204, Yunnan, China.

⁶Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China, Hefei 230027, Anhui, China.

⁷ Center for Evolution and Conservation Biology, Southern Marine Science and Engineering Guangdong Laboratory, Guangzhou 511458, Guangdong, China.

^* Address correspondence to: rlai@mail.kiz.ac.cn (R.L.); myldu@sina.com (Y.M.)

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Received	Accepted	Published
2023-10-30	2023-12-26
Issue Date
2025-07-24

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