ProstaNet: A Novel Geometric Vector Perceptrons–Graph Neural Network Algorithm for Protein Stability Prediction in Single- and Multiple-Point Mutations with Experimental Validation
1Department of Pharmaceutical Sciences, Computational Chemical Genomics Screening Center, and Pharmacometrics and System Pharmacology PharmacoAnalytics, School of Pharmacy, National Center of Excellence for Computational Drug Abuse Research, University of Pittsburgh, Pittsburgh, PA 15261, USA.
2Department of Structural Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
3Department of Medicine, Center for Antibody Therapeutics, Division of Infectious Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
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