Research

Research ›› 2025, Vol. 8 ›› Issue (4) : 0649 . DOI: 10.34133/research.0649

Research Article

EGF-Upregulated lncRNA ESSENCE Promotes Colorectal Cancer Growth through Stabilizing CAD and Ferroptosis Defense

Xiaoshan Xie ¹^,²^,³^,^† ,
Boyu Zhang ¹^,²^,³^,^† ,
Jingxuan Peng ¹^,²^,³ ,
Ning Ma ¹^,²^,³ ,
Qihao Pan ²^,³^,⁴ ,
Yue Wei ¹^,²^,³ ,
Huilin Jin ²^,³^,⁵ ,
Fenghai Yu ¹^,²^,³ ,
Xiaoling Huang ¹^,²^,³ ,
Peng Zhang ¹^,²^,³ ,
Jiarui Wang ¹^,²^,³ ,
Jiaying Zheng ¹^,²^,³ ,
Xiaofang Ying ⁶ ,
Ran-yi Liu ⁷ ,
Hongyan Yu ⁸ ,
Mong-Hong Lee ¹^,²^,³^,^* ,
Xiangqi Meng ¹^,²^,³^,^*

Author information +

¹ Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.

² Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.

³ Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.

⁴ Department of Obstetrics and Gynecology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.

⁵ Department of Hepatobiliary, Pancreatic and Splenic Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510655, China.

⁶ Department of Radiation Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430079, China.

⁷ State Key Laboratory of Oncology in South China & Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.

⁸ Department of Clinical Biological Resource Bank, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China.

^* Address correspondence to: mengxq3@mail.sysu.edu.cn (X.M.); limh33@mail.sysu.edu.cn (M.-H.L.)

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Received	Accepted	Published
2024-09-08	2025-03-08
Issue Date
2025-07-23

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