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In traffic accidents, the results of head injuries resulting from frontal and side impact of vehicles vary significantly, primarily due to the differing impact locations. To investigate the specific effect of impact locations on brain injuries with various impact strengths, experiments are conducted on male rats, focusing on cranial vertex and temporal lobe impact. An experimental protocol is established based on the L₄ (2³) orthogonal table, including impact strength and impact location factors. Rats are injured using the BIMIV rat head impact machine. The effect of impact factors and their levels on TBI is assessed systematically by behavioral performance and pathological findings of key brain regions in rats. The results show that impact strength is the primary factor influencing head injury, but the effect of impact location is not negligible. At the same impact strength, cranial vertex impact is more likely to cause coma, motor and memory deficits, and anxiety than temporal lobe impact. Furthermore, cranial vertex impact results in higher pathological injuries than the nonimpact side of temporal lobe impact, but lower than the impact side. The linear fitting between behavioral performance and pathological results reveals that postinjury behavioral performance in rats more closely aligns with the pathological outcomes on the less injured side of the brain. The findings of this study are crucial for understanding the mechanisms of head injury, proposing appropriate injury evaluation guidelines, and establishing effective protection strategies.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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