Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability
1Department of Medical Oncology, Senior Department of Oncology, the Fifth Medical Center, Chinese PLA General Hospital, Beijing 100853, China
2Department of Thoracic Surgery, Tangdu Hospital, the Fourth Military Medical University, Xi’an 710038, China
3Department of Cardiothoracic Surgery, the 71th Group Army Hospital of PLA, the Affiliated Huaihai Hospital of Xuzhou Medical University, Xuzhou 221004, Jiangsu, China
4Department of Thoracic Surgery, Shaanxi Provincial People's Hospital, the Third Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710068, China
5State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100037, China
6Department of Ophthalmology, Tangdu Hospital, the Fourth Military Medical University, Xi’an 710038, China
7Department of Cardiovascular Surgery, Xijing Hospital, the Fourth Military Medical University, Xi’an 710032, China
收起