Military Medical Research

Military Medical Research ›› 2025, Vol. 12 ›› Issue (4) : 469 - 487. DOI: 10.1186/s40779-024-00533-8

RESEARCH

P. gingivalis in oral-prostate axis exacerbates benign prostatic hyperplasia via IL-6/IL-6R pathway

Shuang-Ying Wang ¹^,^† ,
Yi Cai ¹^,²^,^† ,
Xiao Hu ¹^,²^,^† ,
Fei Li ¹^,² ,
Xin-Hang Qian ¹^,³ ,
Ling-Yun Xia ⁴ ,
Bo Gao ⁵ ,
Lan Wu ⁶ ,
Wen-Zhong Xie ⁷ ,
Jia-Min Gu ¹^,² ,
Tong Deng ¹ ,
Cong Zhu ¹^,² ,
Hai-Chang Jia ¹^,² ,
Wan-Qi Peng ⁶^,⁸ ,
Jiao Huang ¹^,^* ,
Cheng Fang ¹^,^* ,
Xian-Tao Zeng ¹^,²^,^*

Author information +

¹Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, China

²Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China

³Department of Urology, Huaihe Hospital of Henan University, Kaifeng 475000, Henan, China

⁴Department of Stomatology, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China

⁵Department of Laboratory Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China

⁶Department of Stomatology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China

⁷Henan Provincial Engineering Research Center for Microecological Regulatory of Oral Environment and Oral Implantology, Kaifeng University Health Science Center, Kaifeng 475000, Henan, China

⁸School of Stomatology, Jinan University, Guangzhou 510632, China

^* huangjiao1019@163.com;

vitsippa@whu.edu.cn;

zengxiantao1128@163.com

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Issue Date
2025-11-03