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Sleep and memory consolidation
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Bo HU, Xuan TAN
Journal of Army Medical University | 2025, 47(4) : 290 - 297
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Journal of Army Medical University | 2025, 47(4): 290-297
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Sleep and memory consolidation
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Bo HU, Xuan TAN
Affiliations
  • 1Experimental Center of Basic Medicine,College of Basic Medical Sciences,Army Medical University (Third Military Medical University),Chongqing,China
Published: 2025-02-28 doi: 10.16016/j.2097-0927.202504093
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Memory refers to the physiological process in which the brain is able to keep the information obtained from both internal and external sources over an extended period of time. In the brain, neuronal ensembles distributed across multiple regions encode information about past scenes or events and form long-term memories, which then can guide individuals' behavior in similar scenes or events. Unless been consolidated, these newly-formed memories decay quickly. Sleep is a brain state with multiple physiological functions, including non-rapid eye movement sleep (NREM) and rapid eye movement (REM) sleep. Memory formation involves 3 processes: encoding, consolidation, and retrieval. Both reduced sleep time and fragmented sleep can lead to the impaired consolidation of various types of memory, indicating that one of the important physiological functions of sleep is beneficial for the memory consolidation. In this article, we summarizes the critical evidence that NREM sleep and REM sleep are involved in memory consolidation, and discuss how sleep promotes memory consolidation through the mechanisms such as ensemble reactivation and synaptic modification. Future researches may include further exploration on how sleep coordinates synaptic "down-scaling" with "up-scaling", how REM sleep complements with NREM sleep, the involvement of glial cells activity during sleep in memory consolidation, and whether and how brain regions controlling NREM and REM sleep directly participates in the regulation of memory consolidation.

sleep  /  memory consolidation  /  reactivation  /  synaptic plasticity
胡波, 谭萱. 睡眠与记忆巩固. 陆军军医大学学报, 2025 , 47 (4) : 290 -297 . DOI: 10.16016/j.2097-0927.202504093
Bo HU, Xuan TAN. Sleep and memory consolidation[J]. Journal of Army Medical University, 2025 , 47 (4) : 290 -297 . DOI: 10.16016/j.2097-0927.202504093
Year 2025 volume 47 Issue 4
25
11
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doi: 10.16016/j.2097-0927.202504093
  • Receive Date:2025-01-10
  • Online Date:2026-10-30
  • Published:2025-02-28
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  • Received:2025-01-10
  • Revised:2025-02-01
Affiliations
    1Experimental Center of Basic Medicine,College of Basic Medical Sciences,Army Medical University (Third Military Medical University),Chongqing,China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
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Percentage of
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Genus
种数
Number of
species
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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