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An excerpt of Recommendations on drug selection and dose adjustment for patients with liver cirrhosis:Results from a multidisciplinary expert panel (2026)
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Huijuan Xiao1, Tao Han2
Journal of Clinical Hepatology | 2026, 42(8) : 1820 - 1825
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Journal of Clinical Hepatology | 2026, 42(8): 1820-1825
• Guideline •
An excerpt of Recommendations on drug selection and dose adjustment for patients with liver cirrhosis:Results from a multidisciplinary expert panel (2026)
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Huijuan Xiao1, Tao Han2
Affiliations
  • 1Department of Clinical Nutrition,Central Hospital of Tianjin University,Tianjin Third Central Hospital,Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases,Tianjin Artificial Cell Engineering Technology Research Center,Tianjin Institute of Hepatobiliary Disease,Tianjin 300170,China
  • 2Department of Gastroenterology and Hepatology,The First Affiliated Hospital of Nankai University (Tianjin People’s Hospital),Tianjin 300121,China
Published: 2026-08-25 doi: 10.12449/JCH260813
Outline
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Liver cirrhosis profoundly alters drug pharmacokinetics and is frequently associated with medication-related problems in clinical practice. At present,stage-specific medication guidance remains inconsistent,and the information in package inserts often lacks clarity. As a result,treatment decisions rely on individual clinical judgment and differ markedly between different professionals. In 2026,a multidisciplinary expert panel issued recommendation on drug selection and dose adjustment for patients with liver cirrhosis. Using the Delphi method,the suggestion investigates the decisions made by hepatologists,clinical pharmacologists,and clinical pharmacists in terms of drug selection and dose adjustment for liver cirrhosis patients,quantifies the consensus across different Child-Pugh classes,and evaluates the consistency between the recommendations in expert consensus and the information in package inserts,in order to provide a basis for establishing standardized medication guidance. This article gives an excerpt of the main content of the study.

Liver Cirrhosis  /  Pharmaceutical Preparations  /  Practice Guideline
肖慧娟, 韩涛. 《2026年多学科专家小组建议:肝硬化患者药物选择与剂量调整》摘译. 临床肝胆病杂志, 2026 , 42 (8) : 1820 -1825 . DOI: 10.12449/JCH260813
Huijuan Xiao, Tao Han. An excerpt of Recommendations on drug selection and dose adjustment for patients with liver cirrhosis:Results from a multidisciplinary expert panel (2026)[J]. Journal of Clinical Hepatology, 2026 , 42 (8) : 1820 -1825 . DOI: 10.12449/JCH260813
Year 2026 volume 42 Issue 8
124
53
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Article Info
doi: 10.12449/JCH260813
  • Receive Date:2026-04-30
  • Online Date:2026-10-16
  • Published:2026-08-25
Article Data
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History
  • Received:2026-04-30
  • Accepted:2026-05-20
Affiliations
    1Department of Clinical Nutrition,Central Hospital of Tianjin University,Tianjin Third Central Hospital,Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases,Tianjin Artificial Cell Engineering Technology Research Center,Tianjin Institute of Hepatobiliary Disease,Tianjin 300170,China
    2Department of Gastroenterology and Hepatology,The First Affiliated Hospital of Nankai University (Tianjin People’s Hospital),Tianjin 300121,China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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