To explore the acid corrosion resistance of zinc-infiltrated anchor bolt, the corrosion characteristics and mechanical properties of zinc-infiltrated anchor bolt in acidic environment were studied. Firstly, the immersion corrosion tests on ordinary anchor bolts and zinc-infiltrated anchor bolts were carried out, the corrosion kinetic model of zinc-infiltrated anchor bolt was constructed, and the deterioration law of mechanical properties and corrosion failure mechanism of zinc-infiltrated anchor bolt were analyzed. Secondly, the influence of anchor bolt corrosion degradation on the stability of roadway surrounding rocks was analyzed by Abaqus numerical simulation. Finally, the acid corrosion resistance of the zinc-infiltrated anchor bolt was tested by engineering application. The results show that under the same corrosion conditions, the acid corrosion resistance of zinc-infiltrated anchor bolt is significantly better than that of ordinary anchor bolt, and the stability of roadway surrounding rocks supported by zinc-infiltrated anchor bolt is significantly higher than that of ordinary anchor bolt supporting roadway. In the acidic environment, the ordinary anchor bolt is characterized by accelerated corrosion, and the zinc-infiltrated anchor bolt is characterized by uniform corrosion. After corrosion for 100 days, the yield strength, tensile strength and elongation rate of ordinary anchor bolt decrease by 6.50%, 6.37% and 15.85% respectively, and the tensile fracture form changes from ductile fracture to ductile-brittle mixed fracture. The yield strength, tensile strength and elongation rate of the zinc-infiltrated anchor bolt are decreased by 2.85%, 1.45% and 7.97% respectively, and the tensile fracture form is still ductile fracture. After the occurrence of corrosion, the displacement of the roof and two sides of the roadway supported by ordinary anchor bolts is increased by 50.07% and 52.50% respectively, and the stress is increased by 36.85% and 27.41% respectively. The displacement of roof and two sides of roadway supported by zinc-infiltration anchor bolts is increased by 21.07% and 22.06% respectively, and the stress is increased by 16.37% and 20.54% respectively. The results of engineering application show that the use of zinc-infiltration anchor bolt for roadway support can effectively prolong the life of anchorage support and ensure the safety of roadway support.