A FeCoCrNiMn high-entropy alloy (HEA) coating was prepared on the 201 stainless steel surface by adopting high-speed laser cladding technology, and then the microstructure, phase distribution, microhardness of FeCoCrNiMn coating, as well as its wear properties in dry sliding condition were all investigated. It is found that such laser cladded FeCoCrNiMn HEA coating consists of a single FCC structure, with no obvious cracks observed. It also forms a good metallurgical bond with the substrate. The microhardness of the coating is around (439±2.1) HV, nearly two times that of 201 stainless steel substrate, and the strengthening mechanisms mainly include strengthening by grain refinement and solid solution strengthening. Also, the FeCoCrNiMn coating presents an obviously better wear resistance than 201 stainless steel, with an average friction factor of 0.246 and a specific wear rate of about 2.59×10^-6 mm³/(N·m). The wear mechanisms for it include adhesive and abrasive wear. It is concluded that such FeCoCrNiMn HEA coating prepared by high-speed laser cladding technology can significantly improve the surface hardness, wear resistance and service life of machine components.