The objective of the present paper is an attempt to measure the public understanding of science in the area of health and hygiene and test the efficacy of “cultural distance model”. A pre-tested open-ended questionnaire was used for administering cross-sectional surveys at a religio-cultural festival in India. 3484 individuals were interviewed and responses were coded and entered to construct computer database. The data was used for determining the cultural distance of five scientific concepts from the quotidian life of the target population. In developing countries, the formal system of modern education operates as a strong determinant in shaping cultural structures of thoughts prevalent among the citizens. There exists a cultural distance between the scientific structure of configuring natural occurrences and peoples' complexity of thoughts. The distance varies significantly across the concepts that were subjected to the inspection and is a function of the nature of scientific information.