In this paper, 8 SSCI journals in the core collection of WOS database were used as data sources, CiteSpace was used to conduct information visualization analysis on literatures in the field of international biology education from 2000 to 2019, and then the progress, hotspots and trends were systematically reviewed in the field of international biology education in the past two decades. It is found that: (1) the international scientific education community pays more and more attention to biology education; (2) European and American countries dominate the field of research on biology education; (3) the hot spots of research can be clustered into 6 categories, which reflects that international research on biology education focus on the cultivation of scientific literacy, contextualization, timeliness, modernization, and has certain characteristics of cultural uniqueness; and (4) the latest research frontier is about learning progress, evolution and the highest cited literature are curriculum standards. China still has great potential in the field of biology education and science education research. We should put emphasis on implementation of curriculum standards and cultivating students’ core competence. Cooperation should be conducted in- and outside of the country and research should be encouraged to get published abroad. Knowing the international research hotspots and trends, we should focus on the weak areas of existing domestic research and promote the development of local science education.