Plant blindness refers to the inability to see or notice plants in one’s environment, and inability to recognize the importance of plants to the whole biosphere and to human affairs. Plant blindness has become an obstacle of public understanding of plant-based science and engagement in biodiversity conservation. This article reviews the relevant literature regarding plant blindness to explore why this phenomenon occurs and how we can overcome it. It finds that plant blindness is shaped by physiological, educational and cultural features of human being, and the result of the loss of traditional culture as well. It is proved that promoting public’s involvement in building community gardens, innovating plant-based science pedagogy, implementing new techniques in communicating plants, and keeping plants as foreground in urban design are effective approaches to solve the issues caused by the plant blindness. In order to further enhance the plant-based science communication in China, we argue that more empirical studies on plant blindness are needed. Moreover, we should pay attention to the positive role of Chinese traditional culture in public’s understanding of plants, the role that botanical gardens played in science communication. Last but not least, plant blindness could be addressed by the increasing nature education trend, which needs more support from the government.