Currently, science popularization is evolving from the dissemination of scientific knowledge and methods to the promotion of scientific culture and the provision of perceptible, understandable, and resonant experiences for the public. According to Cultural Circuit Theory, the construction of meaning in cultural products is a dynamic process involving the interaction and co-construction of five links:representation, identity, production, consumption, and regulation. This paper discusses how to construct and convey the meaning of scientific culture works from the perspective of Cultural Circuit Theory, based on a series of innovative practices by the China Science and Technology Museum in recent years. It also attempts to distill a methodology with general applicability, namely:starting from in-depth demand insight and meaning presupposition; building a symbolic translation system featuring "storytelling + visualization + experiential engagement + memorable phrasing"; adopting a dual-advisor mechanism of "science + art" and a cross-sector collaborative production model; creating an experiential context of "scene immersion + social interaction + online-offline linkage"; and, through participation and reflection, constructing a value identification chain that progresses from "individuals to groups to the nation." Ultimately, this approach realizes value guidance and internalization within the regulatory framework of the Law of the People's Republic of China on the Popularization of Science and Technology (2024 Revision). This study aims to provide science communicators with new theoretical tools and a culture-based methodology, thereby offering further theoretical references and practical insights for science popularization creation.