Digital economy level evaluation system and Guangzhou urban-rural integration level system were constructed to further calculate the digital economy level and urban-rural integration level in Guangzhou. The following results are obtained: digital economy has a significant positive impact on promoting the integrated development of urban and rural areas in Guangzhou.The improvement of human capital level, urbanization level, the increase of agricultural expenditure, and the narrowing of the gap between urban and rural Engel coefficient can all promote the development of urban-rural integration in Guangzhou, However, although the coefficient of the network traffic density is positive for the urban-rural integration of Guangzhou, But the effect is not obvious.Digital economy promotes the coordinated development of urban and rural areas in Guangzhou through its economic development, capital flow, rural industry revitalization, social security and equalization of public services.