Advanced smart manufacturing factory construction is an important path to fully tap the potential of digital and intelligent technologies in empowering high-quality economic development, and an essential foundation for developing newquality productive forces. Samples are taken from international and domestic advanced smart manufacturing factories across 31 provinces (Due to the lack of data, the statistical data mentioned here do not include the Hong Kong Special Administrative Region, the Macao Special Administrative Region and Taiwan Province.). From the perspective of business environment, the combined method of NCA and fsQCA was adopted to analyze regional differences in the construction of international and domestic advanced smart manufacturing factories affected by multiple concurrent factors. Three key findings are identified. Three identical business environment ecological driving models are confirmed for the efficient construction of both international and domestic advanced smart manufacturing factories, namely the market-driven innovation model, the innovation model relying on finance and law, and the government-assisted innovation model relying on the rule of law and human resources. An asymmetric relationship is found between the business environment driving models for inefficient construction and those for efficient construction of international and domestic advanced smart manufacturing factories. Innovation environment is verified as a core condition in all business environment configurations. Noteworthy theoretical and practical implications are provided for optimizing the business environment to fully stimulate the smart manufacturing vitality of market entities.