As the new round of technological revolution and industrial transformation deepens, the integration of the digital economy and manufacturing has become a key force in driving industrial upgrading. The theoretical framework known as the "techno-economic paradigm" refers to the economic patterns that emerge after technological innovation reshapes the macro and microeconomic structures and operational models. It reveals the evolutionary process through which the digital economy empowers the transformation and upgrading of manufacturing, spanning the stages of "technological system-economic structure-social institution." Although the focus of U. S. policies related to the digital economy may differ, they essentially adhere to the evolutionary logic of the "Techno-Economic Paradigm." These policies revolve around digital top-level design, digital technology development, digital talent training and cultivation, digital collaborative innovation, and the digital ecosystem. The ultimate goal is to drive the evolution of enterprises, industries, and economic systems, thereby achieving the digital transformation and upgrading of the manufacturing sector. In light of the current challenges faced by China's manufacturing industry, efforts to empower manufacturing transformation through the digital economy should focus on strengthening top-level design and policy frameworks, enhancing technological innovation and standards development, bolstering digital talent support, promoting collaborative innovation in all aspects, and building a hierarchy of manufacturing enterprises.