Scientifically identifying the influencing factors of the talents' mobility is the foundation for China to build a world-class talent center and innovation highland, as well as to optimize the regional distribution of talent resources. By analyzing the influencing factors of the academic talents' mobility in China using micro-data of 2004 Changjiang Scholars, the following empirical conclusions can be obtained. A higher level of economic development creates a pull factor, and a higher level of consumption expenditure creates a push factor for the mobility of academic talents. Convenient living and high-quality air create pull factors for the mobility of academic talents. High-ranking institutions are easier to gather talents, but in the areas and institutions with a higher level of innovation development, the academic talents flow more. The academic talents have a strong preference for working in their hometown. At different individual stages, the career development factors and hometown both have a relatively stable influence on the mobility decision, however the economic and social environmental factors are found to have different influences. By revealing the influencing factors of the academic talents' mobility, and the similarities and differences in the impact of various factors at academic talents' different career stages, the researches of the academic talents' mobility have been enriched. Meanwhile, references have been provided for the government to scientifically implement policies to attract academic talents to gather and guide them to flow orderly.