Full
Outline
This study aims to systematically analyze the current situation and causes of drug shortages in multi-level medical institutions in a city in Southern China，as well as their impact on clinical services，so as to provide a scientific basis and policy recommendations for optimizing drug supply chain management and establishing an early warning system for shortages.
Based on 1 272 drug shortage records reported by 109 medical institutions in the city between January 2023 and December 2024，descriptive statistical methods were employed to categorize and organize the data from the dimensions of institution level and pharmacological category. Data were independently collated and verified by two researchers，and Microsoft Excel was used for statistical analysis.
During the research period，a total of 1 272 drug shortage records were reported，involving 54 specific product specifications. Tertiary hospitals ranked the highest in all three aspects: proportion of institutions (34.87%)，number of shortage reports (52.67%)，and number of drug specifications involved (39). In terms of pharmacological categories，cardiovascular system drugs (31.45%)，respiratory system drugs (16.04%)，and nervous system drugs (15.96%) accounted for the highest proportions of shortage reports. The causes of drug shortages，with "other reasons" (28.4%)，price factors (22.1%)，and production discontinuation，output reduction or insufficient production capacity (13.8%) identified as the main contributing factors.
Drug shortages result from the combined effects of market failures，supply chain vulnerabilities，and policy constraints. It is urgent to establish a multi-party collaborative and systematically linked intervention system to improve the stability and accessibility of drug supply.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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