To systematically explore and summarize the research status and hot trends of chronopharmacology from the perspective of bibliometrics，so as to provide meaningful references for the future research in this field.

In this study，relevant articles were collected from Web of Science，and various bibliometric tools were used to conduct corresponding analyses，including publication trends，author and institution collaborations，national (or regional) collaborations，highly cited articles，and keywords which could clarify the research status and hotspots in this field.

A total of 1 762 articles were included，and the research in this field was currently receiving widespread attention from scholars. A total of 589 scholars and 419 institutions worldwide participated in chronopharmacology research，and the research of chronopharmacology had the characteristics of international cooperation. The treatment and efficacy of diseases based on chronopharmacology had always been the research priority in this field，and 10 clusters were obtained through keyword cluster analysis. Meanwhile，the current research hotspots mainly focused on the micro level of disease treatment.

The study of chronopharmacology has certain academic value and clinical significance，with increasing attention from scholars and the emergence of related research hotspots. In the future，research should further grasp the research hotspots and focus on refined research on diseases on the basis of strengthening academic exchanges and cooperation.