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Research Progress on the Pathogenesis of Inflammatory Bowel Disease Complicated with Depression and the Treatment with Traditional Chinese Medicine
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Jiasui HE1a, Jiamei ZHOU1a, Yating YANG1a, Xianjing HU1a, 1b, 2, *
Pharmacy Today | 2026, 36(4) : 315 - 320
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Pharmacy Today | 2026, 36(4): 315-320
Research Progress on the Pathogenesis of Inflammatory Bowel Disease Complicated with Depression and the Treatment with Traditional Chinese Medicine
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Jiasui HE1a, Jiamei ZHOU1a, Yating YANG1a, Xianjing HU1a, 1b, 2, *
Affiliations
  • 1a.Dongguan Key Laboratory of TCM for Prevention and Treatment of Refractory Digestive Diseases, Guangdong Medical University, Dongguan, Guangdong 523808, China
  • 1b.Guangdong Provincial Key Laboratory of Natural Drugs Research and Development, Guangdong Medical University, Dongguan, Guangdong 523808, China
  • 2.Dongguan Key Laboratory of Fundamental Research and Clinical Application of Toxic Chinese Medicine, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong 523121, China
Published: 2026-04-25 doi: 10.12048/j.issn.1674-229X.2026.04.011
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As a special intestinal inflammatory disease, the incidence of anxiety and depression in patients with inflammatory bowel disease (IBD) is much higher than that in normal people. A number of studies have shown a strong correlation between IBD and depression. Based on syndrome differentiation and treatment and starting from the etiology, traditional Chinese medicine (TCM) has better therapeutic efficacy in the treatment of inflammatory bowel disease complicated with depression, and is superior to Western medicine (WM) in improving patients'systemic symptoms as well as reducing side effects. Through literature research and collation, this review aims to discuss and summarize the relationship between IBD and depression as well as the common pathogenesis of IBD complicated with depression in both Western medicine and traditional Chinese medicine, and summarize the TCM treatment methods and curative effects of the disease based on relevant literature, so as to provide reference for the study of the pathogenesis and inspiration for the clinical treatment of the disease.

inflammatory bowel disease  /  depression  /  pathogenesis  /  traditional Chinese medicine
何佳穗, 周家梅, 杨雅婷, 胡显镜. 炎症性肠病合并抑郁症发病机制与中医药治疗研究进展. 今日药学, 2026 , 36 (4) : 315 -320 . DOI: 10.12048/j.issn.1674-229X.2026.04.011
Jiasui HE, Jiamei ZHOU, Yating YANG, Xianjing HU. Research Progress on the Pathogenesis of Inflammatory Bowel Disease Complicated with Depression and the Treatment with Traditional Chinese Medicine[J]. Pharmacy Today, 2026 , 36 (4) : 315 -320 . DOI: 10.12048/j.issn.1674-229X.2026.04.011
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Year 2026 volume 36 Issue 4
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doi: 10.12048/j.issn.1674-229X.2026.04.011
  • Receive Date：2025-08-03
  • Online Date：2026-09-23
  • Published：2026-04-25
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  • Received：2025-08-03
Funding
Affiliations
    1a.Dongguan Key Laboratory of TCM for Prevention and Treatment of Refractory Digestive Diseases, Guangdong Medical University, Dongguan, Guangdong 523808, China
    1b.Guangdong Provincial Key Laboratory of Natural Drugs Research and Development, Guangdong Medical University, Dongguan, Guangdong 523808, China
    2.Dongguan Key Laboratory of Fundamental Research and Clinical Application of Toxic Chinese Medicine, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong 523121, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
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Genus		 种数
Number of
species		 占总种数比例
Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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