To explore the global research progress and future trends of Morinda officinalis How. (Bajitian) from 2000 to 2024.
Using CiteSpace software combined with bibliometric methods, relevant Chinese and English literature on Bajitian were collected from the China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform, VIP Biomedical Database, and Web of Science. Duplicate literatures were eliminated with NoteExpress software, and visual analysis and knowledge graph construction were performed on the publication countries, publication volumes, authors, institutions, keywords, etc., using CiteSpace software.
A total of 2 712 Chinese articles and 374 English articles were included. From 2000 to 2024, the publication volume of research related to Bajitian had steadily increased, and both domestic and international research entered a rapid development stage in 2009. China was the leading country in Bajitian research, and the core domestic research institution was Guangzhou University of Chinese Medicine. Research on Bajitian covered various aspects such as content determination, pharmacological effects, mechanisms of action, and processing methods. Internationally, the focus had been primarily on the pharmacological effects and active ingredients of Bajitian extracts.
Research on Bajitian had entered a diversified development stage, covering multiple aspects including medication rules, chemical constituents, content determination, fingerprint spectrum, famous TCM physician experience, and clinical application. After 2020, studies using data mining, network pharmacology, and other technologies for molecular docking and mechanisms of action have become a research hotspot, mainly focusing on anti-inflammation, anti-depression, anti-osteoporosis, anti-oxidation, and the treatment of ovarian and testicular dysfunction.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |