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Analysis of Off-Label Use of Pregabalin in Outpatient Clinics at A Dermatology Specialist Hospital
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Changzhen LI1, Zhiyuan FU1, Xiaobing WANG2, *
Pharmacy Today | 2026, 36(3) : 219 - 223
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Pharmacy Today | 2026, 36(3): 219-223
Analysis of Off-Label Use of Pregabalin in Outpatient Clinics at A Dermatology Specialist Hospital
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Changzhen LI1, Zhiyuan FU1, Xiaobing WANG2, *
Affiliations
  • 1.Dermatology Hospital of Jiangxi Province, Nanchang, Jiangxi 330001, China
  • 2.Jiangxi Provincial Clinical Research Center For Skin Diseases, Nanchang, Jiangxi 330001, China
Published: 2026-03-25 doi: 10.12048/j.issn.1674-229X.2026.03.010
Outline
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OBJECTIVE

To investigate the off-label use of pregabalin in the outpatient department of a hospital, analyze the types, reasons, and potential risks of such usage, and provide reference for improving the safety and rationality of its use.

METHODS

A total of 2 183 outpatient prescriptions containing pregabalin issued between May 2023 and April 2024 were selected.Patient basic information, demographics, clinical diagnoses, and concomitant medications were recorded.

RESULTS

Among the 2 183 prescriptions, 421 (19.29%) involved off-label use.The primary categories included off-label indications (94.06%), off-label patient populations (1.66%), and concomitant medications (4.28%). Additionally, 281 prescriptions (12.87%) were deemed irrational, mainly due to inappropriate indications (26 cases) and altered dosing frequency (255 cases).

CONCLUSION

Off-label use of pregabalin is prevalent in the dermatology outpatient department of the hospital. However, significant irrational prescribing practices exist.The hospital should refine and enforce relevant systems, enhance physician training and patient education, and conduct in‐depth specialized prescription reviews and risk assessments to ensure medication safety and rational use.

pregabalin  /  off-label drug use  /  itch  /  rational use of medicines
李嫦珍, 付志媛, 王小兵. 皮肤病专科医院门诊普瑞巴林超说明书用药情况分析. 今日药学, 2026 , 36 (3) : 219 -223 . DOI: 10.12048/j.issn.1674-229X.2026.03.010
Changzhen LI, Zhiyuan FU, Xiaobing WANG. Analysis of Off-Label Use of Pregabalin in Outpatient Clinics at A Dermatology Specialist Hospital[J]. Pharmacy Today, 2026 , 36 (3) : 219 -223 . DOI: 10.12048/j.issn.1674-229X.2026.03.010
Appendix
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Year 2026 volume 36 Issue 3
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Article Info
doi: 10.12048/j.issn.1674-229X.2026.03.010
  • Receive Date：2025-04-24
  • Online Date：2026-09-23
  • Published：2026-03-25
Article Data
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History
  • Received：2025-04-24
Funding
Affiliations
    1.Dermatology Hospital of Jiangxi Province, Nanchang, Jiangxi 330001, China
    2.Jiangxi Provincial Clinical Research Center For Skin Diseases, Nanchang, Jiangxi 330001, China
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https://castjournals.cast.org.cn/joweb/jryx/EN/10.12048/j.issn.1674-229X.2026.03.010
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表12种不同金属材料的力学参数
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Family		 属数
Number of
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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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