The ongoing commercialization of genetically modified (GM) crops continues to enhance global grain yields, improve crop quality, and reduce pesticide usage. These technological advancements have effectively propelled agricultural production systems toward sustainable transformation. Specifically, GM crops address core challenges such as pest infestations, weed proliferation, and arable land constraints, emerging as a pivotal new productive force in agriculture. This study systematically examines the global spatial distribution patterns of GM crops in 2024 and provides an indepth analysis of the driving forces and evolving regional trends, offering critical informational support and strategic guidance for innovation in agricultural science and technology. In 2024, the global GM crop cultivation area reached 209.8 million hectares, a 1.7% year-on-year increase. GM Glycine max (soybean) and Zea mays (maize) dominated the landscape, accounting for 50.0 and 32.5% of the total area, respectively. Among them, maize with stacked traits of insect resistance and herbicide tolerance accounts for 92.5% of GM maize. The share of cultivation in developing countries expanded substantially, with Brazil and Vietnam emerging as regional growth drivers. Policy support and the diffusion of advanced technologies were identified as core driving forces. Concurrently, applications of gene-editing technology accelerated, and several countries approved novel tr aits such as drought tolerance and disease resistance, marking substantial progress in the commercialization of next-generation GM crops. This research provides multidimensional insights and strategic guidance to support global agricultural biotechnology development, promoting the transition of biotechnology breeding into the ‘4.0 era’.