Article(id=1203057880288157719, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1203057879566737430, articleNumber=null, orderNo=null, doi=10.11855/j.issn.0577-7402.2023.02.0123, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=research-article, receivedDate=1674057600000, receivedDateStr=2023-01-19, revisedDate=null, revisedDateStr=null, acceptedDate=1674835200000, acceptedDateStr=2023-01-28, onlineDate=1764760950395, onlineDateStr=2025-12-03, pubDate=1677513600000, pubDateStr=2023-02-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1764760950395, onlineIssueDateStr=2025-12-03, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1764760950395, creator=13701087609, updateTime=1764760950395, updator=13701087609, issue=Issue{id=1203057879566737430, tenantId=1146029695717560320, journalId=1189873630562394117, year='2023', volume='48', issue='2', pageStart='123', pageEnd='244', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1764760950222, creator=13701087609, updateTime=1764762101198, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1203062707223241334, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1203057879566737430, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1203062707223241335, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1203057879566737430, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=123, endPage=131, ext={EN=ArticleExt(id=1203057881592586267, articleId=1203057880288157719, tenantId=1146029695717560320, journalId=1189873630562394117, language=EN, title=Expert recommendations for clinical diagnosis and treatment of coronavirus disease 2019 induced neurological diseases, columnId=1190310109461971339, journalTitle=Medical Journal of Chinese People’s Liberation Army, columnName=Guideline and Consensus, runingTitle=null, highlight=null, articleAbstract=

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly infectious and pathogenic.Although it mainly involves the respiratory system, it can also invade the nervous system and lead to a variety of neurological symptoms and diseases, further complicating the clinical conditions of the patients. In order to assist physicians and neurologists in understanding the pathogenesis, clinical features, diagnostic procedures, therapeutic principles, and clinical outcomes of the diseases,the experts of Neurology Branch of Chinese Medical Doctor Association wrote this expert recommendation based on present research articles and clinical practices about the epidemiology, clinical symptoms, diagnostic algorithms, treatment and prognosis of neurological diseases caused by coronavirus disease 2019, in order to provide reference for clinical diagnosis and treatment.

, correspAuthors=null, authorNote=null, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, authorCompany=null, fund=null, authors=null, authorsList=Neurology Branch of Chinese Medical Doctor Association), CN=ArticleExt(id=1203057882657939506, articleId=1203057880288157719, tenantId=1146029695717560320, journalId=1189873630562394117, language=CN, title=新型冠状病毒感染所致神经系统疾病临床救治专家推荐意见, columnId=1190310109688463760, journalTitle=解放军医学杂志, columnName=指南与共识, runingTitle=null, highlight=null, articleAbstract=

新型冠状病毒（SARS-CoV-2）具有高度传染性及致病性，主要累及呼吸系统，也可侵犯神经系统引发多种神经症状及疾病，进一步导致部分患者症状及病情复杂化。为使广大一线医疗工作者了解此类疾病的发病机制、临床特征、诊治要点及临床转归，中国医师协会神经内科医师分会组织专家依据国内外现有研究报道及临床经验，就疾病流行特点、神经系统损害常见症状、疾病类型、诊断流程、治疗及预后的相关要点等进行讨论并撰写了此推荐意见，以期为临床诊疗工作提供参考。

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ACE2. 血管紧张素转化酶2；A. 新冠病毒S蛋白与细胞膜表面的ACE2受体结合侵入细胞；B. 病毒通过血脑屏障转运进入中枢神经系统；C. 病毒沿嗅神经/三叉神经通路进入神经系统，并可经跨突触逆行运输而扩散；D. 病毒与周围神经轴突、髓鞘及肌肉细胞上的ACE2受体结合

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