Article(id=1198623859374125874, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1198619422425448948, articleNumber=null, orderNo=null, doi=10.11855/j.issn.0577-7402.1326.2024.0126, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=research-article, receivedDate=1696694400000, receivedDateStr=2023-10-08, revisedDate=null, revisedDateStr=null, acceptedDate=1700064000000, acceptedDateStr=2023-11-16, onlineDate=1763703797428, onlineDateStr=2025-11-21, pubDate=1716825600000, pubDateStr=2024-05-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1763703797428, onlineIssueDateStr=2025-11-21, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1763703797428, creator=13701087609, updateTime=1763703797428, updator=13701087609, issue=Issue{id=1198619422425448948, tenantId=1146029695717560320, journalId=1189873630562394117, year='2024', volume='49', issue='5', pageStart='489', pageEnd='610', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1763702739578, creator=13701087609, updateTime=1763702927730, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1198620211667628088, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1198619422425448948, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1198620211667628089, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1198619422425448948, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=534, endPage=541, ext={EN=ArticleExt(id=1198623859642561332, articleId=1198623859374125874, tenantId=1146029695717560320, journalId=1189873630562394117, language=EN, title=Epidemiological and clinical characteristics of 954 cases of infectious diseases of central nervous system in Chongqing, columnId=1190310109000602400, journalTitle=Medical Journal of Chinese People’s Liberation Army, columnName=Clinical Research, runingTitle=null, highlight=null, articleAbstract=
Objective To investigate the epidemiological and clinical characteristics of 954 cases of central nervous system (CNS) infections in Chongqing. Methods A retrospective analysis was conducted on 954 patients with CNS infectious disease diagnosed and treated in the Second Affiliated Hospital of Army Medical University from 2008 to 2021. The analysis encompassed pathogens, patient gender, age of onset, time of onset, urban-rural distribution, education level, occupational distribution, and other epidemiological characteristics. The clinical manifestations, the positive rate of metagenomic next-generation sequencing (mNGS), and prognosis were also analyzed. ResultsAmong the 945 cases of CNS infectious diseases, the pathogens were viruses in 393(41.2%), Mycobacterium tuberculosis in 361(37.8%), other bacteria in 108(11.3%), Cryptococcus in 75(7.9%), Treponema pallidum in 16(1.7%) and parasites in 1(0.1%). The number of CNS infection cases from 2015 to 2021 increased by 85.6% compared with that from 2008 to 2014 (620 vs. 334, P<0.001). There was no significant difference in seasonal distribution of pathogens (P>0.05). CNS infectious diseases were more prevalent in rural areas (58.0%, P<0.001), with a male-to-female ratio of 1.7:1.0, and a higher incidence in individuals aged between 35 and 60 years. The majority of patients were educated at Junior high school level or below (68.7%) and were farmers or workers (68.1%). Clinical symptoms of CNS infectious disease mainly included fever, headache, signs of meningeal irritation, nausea and vomiting, which could be accompanied by consciousness disorder and focal neurological deficits. mNGS significantly improves the accuracy of clinical diagnosis. The rate of good prognosis of CNS infectious diseases was 97.5%, while the mortality rate was 0.3%. Conclusions In Chongqing area, the categories and species of CNS infectious pathogens are diverse, widely prevalent, and the clinical manifestations are complex. Moreover, the number of cases has been increasing in recent years. Understanding the epidemiological and clinical characteristics of CNS infectious diseases can help to recognize the regional differences, promote early accurate diagnosis and treatment, and improve prognosis.
, correspAuthors=Wen Huang, authorNote=null, correspAuthorsNote=
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954例中枢神经系统感染性疾病的流行病学和临床特征分析, columnId=1190310109164180259, journalTitle=解放军医学杂志, columnName=临床研究, runingTitle=null, highlight=null, articleAbstract=
目的 探讨重庆地区954例中枢神经系统(CNS)感染性疾病的流行病学及临床特征。方法 回顾性分析2008—2021年重庆新桥医院诊治的954例CNS感染性疾病的病原体与患者性别、发病年龄与时间、城乡分布、受教育程度、职业分布等流行病学特点，以及临床表现、宏基因组学第二代测序(mNGS)的阳性率和预后等临床特征。结果 954例CNS感染性疾病的病原体为病毒393例(41.2%)、结核分枝杆菌361例(37.8%)、其他细菌108例(11.3%)、隐球菌75例(7.9%)、梅毒螺旋体16例(1.7%)、寄生虫1例(0.1%)；2015-2021年的CNS感染病例数较2008-2014年增加85.6%(620 vs. 334，P<0.001)；不同病原体的季节分布差异无统计学意义(P>0.05)；CNS感染性疾病好发于农村(58.0%，P<0.001)，男女比例为1.7:1.0，35~60岁发病较多；CNS感染性疾病多见于学历为初中及以下(68.7%)和职业为农民或工人(68.1%)的群体；临床症状以发热、头痛、脑膜刺激征及恶心呕吐等脑膜受累症状为主，可伴有意识改变、局灶神经功能缺损症状等表现；mNGS明显提高了临床诊断精准性；疾病良好预后率为97.5%，病死率为0.3%。结论 重庆地区CNS感染病原体类别及种属多样、流行面广、临床表现复杂，且近年来病例数目呈上升趋势。了解当地CNS感染性疾病的流行病学和临床特征有助于了解疾病的区域差异，促进疾病的早期精准诊断、治疗，并改善预后。
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张兰，硕士研究生，主要从事中枢神经系统感染及血管性认知障碍等方面的研究
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Robertson F C,
Lepard J R,
Mekary R A, et al. Epidemiology of central nervous system infectious diseases: a meta-analysis and systematic review with implications for neurosurgeons worldwide[J].
J Neurosurgery,
2018,
130(4): 1107-1126., articleTitle=Epidemiology of central nervous system infectious diseases: a meta-analysis and systematic review with implications for neurosurgeons worldwide, refAbstract=null), Reference(id=1198684437564195148, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2022, volume=47, issue=11, pageStart=1125, pageEnd=1132, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=韩慰, 蒋莉, 洪思琦, journalName=解放军医学杂志, refType=null, unstructuredReference=韩慰, 蒋莉, 洪思琦, 等. 儿童重症抗NMDAR脑炎的临床特征、治疗及预后分析[J].
解放军医学杂志,
2022,
47(11): 1125-1132., articleTitle=儿童重症抗NMDAR脑炎的临床特征、治疗及预后分析, refAbstract=null), Reference(id=1198684437631304013, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2022, volume=32, issue=4, pageStart=241, pageEnd=249, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=黄姗姗, 周伍明, 汪敏捷, journalName=医学新知, refType=null, unstructuredReference=黄姗姗, 周伍明, 汪敏捷, 等. 1990年与2019年中国病毒性脑炎疾病负担分析[J].
医学新知,
2022,
32(4): 241-249., articleTitle=1990年与2019年中国病毒性脑炎疾病负担分析, refAbstract=null), Reference(id=1198684437690024270, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2020, volume=395, issue=10232, pageStart=1230, pageEnd=null, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=Lancet T, journalName=Lancet (London, England), refType=null, unstructuredReference=
Lancet T. A new roadmap for meningitis[J].
Lancet (London, England),
2020,
395(10232): 1230., articleTitle=A new roadmap for meningitis, refAbstract=null), Reference(id=1198684437815853391, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2023, volume=22, issue=8, pageStart=685, pageEnd=711, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=GBD 2019 Meningitis Antimicrobial Resistance Collaborators, journalName=Lancet Neurol, refType=null, unstructuredReference=GBD 2019 Meningitis Antimicrobial Resistance Collaborators. Global, regional, and national burden of meningitis and its aetiologies, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019[J].
Lancet Neurol,
2023,
22(8): 685-711., articleTitle=Global, regional, and national burden of meningitis and its aetiologies, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019, refAbstract=null), Reference(id=1198684437912322384, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2021, volume=16, issue=5, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[6], rfOrder=5, authorNames=Bumburidi Y, Utepbergenova G, Yerezhepov B, journalName=PLoS One, refType=null, unstructuredReference=
Bumburidi Y,
Utepbergenova G,
Yerezhepov B, et al. Etiology of acute meningitis and encephalitis from hospital-based surveillance in South Kazakhstan oblast, February 2017-January 2018[J].
PLoS One,
2021,
16(5): e251494., articleTitle=Etiology of acute meningitis and encephalitis from hospital-based surveillance in South Kazakhstan oblast, February 2017-January 2018, refAbstract=null), Reference(id=1198684437975236945, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2019, volume=18, issue=8, pageStart=771, pageEnd=783, url=null, language=null, rfNumber=[7], rfOrder=6, authorNames=Donovan J, Figaji A, Imran D, journalName=Lancet Neurol, refType=null, unstructuredReference=
Donovan J,
Figaji A,
Imran D, et al. The neurocritical care of tuberculous meningitis[J].
Lancet Neurol,
2019,
18(8): 771-783., articleTitle=The neurocritical care of tuberculous meningitis, refAbstract=null), Reference(id=1198684438046540114, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2021, volume=34, issue=3, pageStart=386, pageEnd=395, url=null, language=null, rfNumber=[8], rfOrder=7, authorNames=Wall EC, Chan JM, Gil E, journalName=Current Opin Neurol, refType=null, unstructuredReference=
Wall EC,
Chan JM,
Gil E, et al. Acute bacterial meningitis[J].
Current Opin Neurol,
2021,
34(3): 386-395., articleTitle=Acute bacterial meningitis, refAbstract=null), Reference(id=1198684438117843283, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2019, volume=150, issue=2, pageStart=117, pageEnd=130, url=null, language=null, rfNumber=[9], rfOrder=8, authorNames=Daniel BD, Grace GA, Natrajan M, journalName=Indian J Med Res, refType=null, unstructuredReference=
Daniel BD,
Grace GA,
Natrajan M.
Tuberculous meningitis in children: clinical management & outcome[J].
Indian J Med Res,
2019,
150(2): 117-130., articleTitle=
Tuberculous meningitis in children: clinical management & outcome, refAbstract=null), Reference(id=1198684438184952148, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2018, volume=36, issue=2, pageStart=65, pageEnd=68, url=null, language=null, rfNumber=[10], rfOrder=9, authorNames=鲁雁秋, 黄晓婕, 刘敏, journalName=中华传染病杂志, refType=null, unstructuredReference=鲁雁秋, 黄晓婕, 刘敏, 等. 重庆地区499例艾滋病合并中枢神经系统感染患者的疾病谱及预后影响因素分析[J].
中华传染病杂志,
2018,
36(2): 65-68., articleTitle=重庆地区499例艾滋病合并中枢神经系统感染患者的疾病谱及预后影响因素分析, refAbstract=null), Reference(id=1198684438247866709, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2008, volume=null, issue=null, pageStart=2, pageEnd=null, url=null, language=null, rfNumber=[11], rfOrder=10, authorNames=世界卫生组织, journalName=疾病和有关健康问题的国际统计分类: 第十次修订本, refType=null, unstructuredReference=世界卫生组织.
疾病和有关健康问题的国际统计分类: 第十次修订本[M]. 2 版. 董景五, 译. 北京: 人民卫生出版社,
2008., articleTitle=null, refAbstract=null), Reference(id=1198684438335947094, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2010, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[12], rfOrder=11, authorNames=Marais S, Thwaites G, Schoeman JF, journalName=10, refType=null, unstructuredReference=
Marais S,
Thwaites G,
Schoeman JF, et al.
Tuberculous meningitis: a uniform case definition for use in clinical research[Z].
2010:
10, 803-812., articleTitle=
Tuberculous meningitis: a uniform case definition for use in clinical research, refAbstract=null), Reference(id=1198684438419833175, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=4, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[13], rfOrder=12, authorNames=吕传真, 周良辅, journalName=实用神经病学, refType=null, unstructuredReference=吕传真, 周良辅.
实用神经病学[M].
4 版. 上海: 上海科学技术出版社, 2014., articleTitle=null, refAbstract=null), Reference(id=1198684438482747736, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2023, volume=39, issue=6, pageStart=72, pageEnd=77, url=null, language=null, rfNumber=[14], rfOrder=13, authorNames=王兴宇, 马立聪, 常燕琴, journalName=包头医学院学报, refType=null, unstructuredReference=王兴宇, 马立聪, 常燕琴, 等. 2014-2021年中老年群体中枢神经系统感染流行性特征及耐药性分析[J].
包头医学院学报,
2023,
39(6): 72-77., articleTitle=2014-2021年中老年群体中枢神经系统感染流行性特征及耐药性分析, refAbstract=null), Reference(id=1198684438545662297, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2017, volume=74, issue=1, pageStart=1, pageEnd=9, url=null, language=null, rfNumber=[15], rfOrder=14, authorNames=Khatib U, van de Beek D, Lees JA, journalName=J Infect, refType=null, unstructuredReference=
Khatib U,
van de Beek D,
Lees JA, et al. Adults with suspected central nervous system infection: a prospective study of diagnostic accuracy[J].
J Infect,
2017,
74(1): 1-9., articleTitle=Adults with suspected central nervous system infection: a prospective study of diagnostic accuracy, refAbstract=null), Reference(id=1198684438612771162, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2019, volume=23, issue=8, pageStart=1604, pageEnd=1607, url=null, language=null, rfNumber=[16], rfOrder=15, authorNames=高建国, journalName=安徽医药, refType=null, unstructuredReference=高建国. 中枢神经系统感染性疾病的流行特征分析[J].
安徽医药,
2019,
23(8): 1604-1607., articleTitle=中枢神经系统感染性疾病的流行特征分析, refAbstract=null), Reference(id=1198684438679880027, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2013, volume=39, issue=9, pageStart=548, pageEnd=552, url=null, language=null, rfNumber=[17], rfOrder=16, authorNames=邹月丽, 王轩, 何俊瑛, journalName=中国神经精神疾病杂志, refType=null, unstructuredReference=邹月丽, 王轩, 何俊瑛, 等. 石家庄及其周边地区常见中枢神经系统感染的现状分析[J].
中国神经精神疾病杂志,
2013,
39(9): 548-552., articleTitle=石家庄及其周边地区常见中枢神经系统感染的现状分析, refAbstract=null), Reference(id=1198684438772154716, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2019, volume=30, issue=4, pageStart=8, pageEnd=11, url=null, language=null, rfNumber=[18], rfOrder=17, authorNames=陈凡, 朱荣生, 周菁, journalName=公共卫生与预防医学, refType=null, unstructuredReference=陈凡, 朱荣生, 周菁, 等. 我国结核病防治现状与展望[J].
公共卫生与预防医学,
2019,
30(4): 8-11., articleTitle=我国结核病防治现状与展望, refAbstract=null), Reference(id=1198684438897983837, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2023, volume=49, issue=1, pageStart=43, pageEnd=49, url=null, language=null, rfNumber=[19], rfOrder=18, authorNames=赵家华, 岑雨樱, 许晓娇, journalName=解放军医学杂志, refType=null, unstructuredReference=赵家华, 岑雨樱, 许晓娇, 等. 1247例中枢神经系统感染性疾病的流行病学及临床特征: 一项单中心回顾性分析[J].
解放军医学杂志,
2023,
49(1): 43-49., articleTitle=1247例中枢神经系统感染性疾病的流行病学及临床特征: 一项单中心回顾性分析, refAbstract=null), Reference(id=1198684438986064222, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2013, volume=31, issue=11, pageStart=663, pageEnd=666, url=null, language=null, rfNumber=[20], rfOrder=19, authorNames=杨进孙, 王文节, 葛宗成, journalName=中华传染病杂志, refType=null, unstructuredReference=杨进孙, 王文节, 葛宗成, 等. 中枢神经系统感染患者两个 10 年的临床特征对比分析[J].
中华传染病杂志,
2013,
31(11): 663-666., articleTitle=中枢神经系统感染患者两个 10 年的临床特征对比分析, refAbstract=null), Reference(id=1198684439048978783, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2023, volume=26, issue=6, pageStart=731, pageEnd=736, url=null, language=null, rfNumber=[21], rfOrder=20, authorNames=祖向阳, 冯森, 马鹏, journalName=中国实用神经疾病杂志, refType=null, unstructuredReference=祖向阳, 冯森, 马鹏. 颅内动脉瘤术后中枢神经系统感染患者脑脊液病原菌分布药敏试验及耐药基因分析[J].
中国实用神经疾病杂志,
2023,
26(6): 731-736., articleTitle=颅内动脉瘤术后中枢神经系统感染患者脑脊液病原菌分布药敏试验及耐药基因分析, refAbstract=null), Reference(id=1198684439111893344, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2021, volume=14, issue=null, pageStart=2091, pageEnd=2103, url=null, language=null, rfNumber=[22], rfOrder=21, authorNames=Zhou T, Kuang M, Huang S, journalName=Infect Drug Resist, refType=null, unstructuredReference=
Zhou T,
Kuang M,
Huang S, et al. Epidemiological characteristics and drug resistance analysis of cerebrospinal fluid microbial infections in Wenzhou Area[J].
Infect Drug Resist,
2021,
14: 2091-2103., articleTitle=Epidemiological characteristics and drug resistance analysis of cerebrospinal fluid microbial infections in Wenzhou Area, refAbstract=null), Reference(id=1198684439183196513, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2019, volume=39, issue=3, pageStart=383, pageEnd=390, url=null, language=null, rfNumber=[23], rfOrder=22, authorNames=Agnihotri S P, journalName=Semin Neurol, refType=null, unstructuredReference=
Agnihotri S P. Central nervous system opportunistic infections[J].
Semin Neurol,
2019,
39(3): 383-390., articleTitle=Central nervous system opportunistic infections, refAbstract=null), Reference(id=1198684439271276898, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2021, volume=54, issue=12, pageStart=1234, pageEnd=1240, url=null, language=null, rfNumber=[24], rfOrder=23, authorNames=中华医学会神经病学分会感染性疾病与脑脊液细胞学学组, journalName=中华神经科杂志, refType=null, unstructuredReference=中华医学会神经病学分会感染性疾病与脑脊液细胞学学组. 中枢神经系统感染性疾病的脑脊液宏基因组学第二代测序应用专家共识[J].
中华神经科杂志,
2021,
54(12): 1234-1240., articleTitle=中枢神经系统感染性疾病的脑脊液宏基因组学第二代测序应用专家共识, refAbstract=null), Reference(id=1198684439350968675, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2022, volume=39, issue=11, pageStart=845, pageEnd=849, url=null, language=null, rfNumber=[25], rfOrder=24, authorNames=王余成, 周晋, journalName=中国消毒学杂志, refType=null, unstructuredReference=王余成, 周晋. 477例中枢神经系统感染脑脊液培养阳性患者的临床特征及病原菌耐药性分析[J].
中国消毒学杂志,
2022,
39(11): 845-849., articleTitle=477例中枢神经系统感染脑脊液培养阳性患者的临床特征及病原菌耐药性分析, refAbstract=null), Reference(id=1198684439422271844, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2022, volume=47, issue=4, pageStart=393, pageEnd=398, url=null, language=null, rfNumber=[26], rfOrder=25, authorNames=张嫘, 耿荣华, 蔡珍, journalName=中国抗生素杂志, refType=null, unstructuredReference=张嫘, 耿荣华, 蔡珍,等. 中枢神经系统感染患者的临床及病原学特征研究[J].
中国抗生素杂志,
2022,
47(4): 393-398., articleTitle=中枢神经系统感染患者的临床及病原学特征研究, refAbstract=null), Reference(id=1198684439489380709, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2021, volume=34, issue=3, pageStart=238, pageEnd=244, url=null, language=null, rfNumber=[27], rfOrder=26, authorNames=Bloch K, Hasbun R, journalName=Curr Opin Infect Dis, refType=null, unstructuredReference=
Bloch K,
Hasbun R. Central nervous system infections associated with neurologic devices[J].
Curr Opin Infect Dis,
2021,
34(3): 238-244., articleTitle=Central nervous system infections associated with neurologic devices, refAbstract=null), Reference(id=1198684439569072486, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2022, volume=49, issue=19, pageStart=3457, pageEnd=3461, url=null, language=null, rfNumber=[28], rfOrder=27, authorNames=李建琼, 吴成果, 张婷, journalName=现代预防医学, refType=null, unstructuredReference=李建琼, 吴成果, 张婷, 等. 2011-2020年重庆市结核病防治经费投入与效益产出分析[J].
现代预防医学,
2022,
49(19): 3457-3461., articleTitle=2011-2020年重庆市结核病防治经费投入与效益产出分析, refAbstract=null), Reference(id=1198684439631987047, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2017, volume=31, issue=7, pageStart=4, pageEnd=null, url=null, language=null, rfNumber=[29], rfOrder=28, authorNames=高彩云, 申希平, 丁国武, journalName=中国初级卫生保健, refType=null, unstructuredReference=高彩云, 申希平, 丁国武. 2009-2014年西北地区脑炎、脑膜炎症候群监测病例流行特征分析[J].
中国初级卫生保健,
2017,
31(7): 4., articleTitle=2009-2014年西北地区脑炎、脑膜炎症候群监测病例流行特征分析, refAbstract=null), Reference(id=1198684439690707304, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2013, volume=35, issue=4, pageStart=599, pageEnd=601, url=null, language=null, rfNumber=[30], rfOrder=29, authorNames=韩冰, 王志红, 王明栋, journalName=河北医药, refType=null, unstructuredReference=韩冰, 王志红, 王明栋, 等. 河北省中南部地区成人中枢神经系统感染性疾病流行病学分析[J].
河北医药,
2013,
35(4): 599-601., articleTitle=河北省中南部地区成人中枢神经系统感染性疾病流行病学分析, refAbstract=null), Reference(id=1198684439749427561, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2016, volume=25, issue=null, pageStart=9, pageEnd=null, url=null, language=null, rfNumber=[31], rfOrder=30, authorNames=Nuoh R D, Nyarko K M, Nortey P, journalName=Pan Afric Med J, refType=null, unstructuredReference=
Nuoh R D,
Nyarko K M,
Nortey P, et al. Review of meningitis surveillance data, upper West Region, Ghana 2009-2013[J].
Pan Afric Med J,
2016,
25(Suppl 1): 9., articleTitle=Review of meningitis surveillance data, upper West Region, Ghana 2009-2013, refAbstract=null), Reference(id=1198684439816536426, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2021, volume=36, issue=22, pageStart=5182, pageEnd=5185, url=null, language=null, rfNumber=[32], rfOrder=31, authorNames=谭琪琪, 晏翠芳, 王梓宸, journalName=中国妇幼保健, refType=null, unstructuredReference=谭琪琪, 晏翠芳, 王梓宸, 等. 广州地区儿童病毒性中枢神经系统感染病毒谱分析[J].
中国妇幼保健,
2021,
36(22): 5182-5185., articleTitle=广州地区儿童病毒性中枢神经系统感染病毒谱分析, refAbstract=null), Reference(id=1198684439892033899, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2021, volume=30, issue=8, pageStart=119, pageEnd=120, url=null, language=null, rfNumber=[33], rfOrder=32, authorNames=张天翔, 张雪云, 杨淼, journalName=武警后勤学院学报(医学版), refType=null, unstructuredReference=张天翔, 张雪云, 杨淼. 中枢神经系统感染临床特征及病原学特点[J].
武警后勤学院学报(医学版),
2021,
30(8): 119-120., articleTitle=中枢神经系统感染临床特征及病原学特点, refAbstract=null), Reference(id=1198684440252744044, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2019, volume=40, issue=4, pageStart=417, pageEnd=421, url=null, language=null, rfNumber=[34], rfOrder=33, authorNames=郭建花, 李静, 张欣, journalName=中华流行病学杂志, refType=null, unstructuredReference=郭建花, 李静, 张欣. 石家庄市2007-2017年18岁以下人群急性脑炎脑膜炎流行趋势[J].
中华流行病学杂志,
2019,
40(4): 417-421., articleTitle=石家庄市2007-2017年18岁以下人群急性脑炎脑膜炎流行趋势, refAbstract=null), Reference(id=1198684440324047213, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2015, volume=10, issue=12, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[35], rfOrder=34, authorNames=Xie Y, Tan Y, Chongsuvivatwong V, journalName=PLoS One, refType=null, unstructuredReference=
Xie Y,
Tan Y,
Chongsuvivatwong V, et al. A population-based acute meningitis and encephalitis syndromes surveillance in Guangxi, China, May 2007-June 2012[J].
PLoS One,
2015,
10(12): e144366., articleTitle=A population-based acute meningitis and encephalitis syndromes surveillance in Guangxi, China, May 2007-June 2012, refAbstract=null), Reference(id=1198684440395350382, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2022, volume=3, issue=4, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[36], rfOrder=35, authorNames=Puka K, Buckley C, Mulia N, journalName=JAMA Health Forum, refType=null, unstructuredReference=
Puka K,
Buckley C,
Mulia N, et al. Educational attainment and lifestyle risk factors associated with all-cause mortality in the US[J].
JAMA Health Forum,
2022,
3(4): e220401., articleTitle=Educational attainment and lifestyle risk factors associated with all-cause mortality in the US, refAbstract=null), Reference(id=1198684440466653551, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2016, volume=4, issue=3, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[37], rfOrder=36, authorNames=Zimmer AJ, Burke VE, Bloch KC, journalName=Microbiol Spectr, refType=null, unstructuredReference=
Zimmer AJ,
Burke VE,
Bloch KC. Central nervous system infections[J].
Microbiol Spectr,
2016,
4(3). doi:
10.1128/microbiolspec.DMIH2-0012-2015., articleTitle=Central nervous system infections, refAbstract=null), Reference(id=1198684440554733936, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2022, volume=31, issue=1, pageStart=45, pageEnd=48, url=null, language=null, rfNumber=[38], rfOrder=37, authorNames=陈菲菲, 刘青侠, journalName=癫痫与神经电生理学杂志, refType=null, unstructuredReference=陈菲菲, 刘青侠. 基于单中心的中枢神经系统感染的疾病谱及预后分析[J].
癫痫与神经电生理学杂志,
2022,
31(1): 45-48., articleTitle=基于单中心的中枢神经系统感染的疾病谱及预后分析, refAbstract=null), Reference(id=1198684440638620017, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2016, volume=16, issue=7, pageStart=397, pageEnd=403, url=null, language=null, rfNumber=[39], rfOrder=38, authorNames=王娜, 张馨月, 张吴琼, journalName=中国现代神经疾病杂志, refType=null, unstructuredReference=王娜, 张馨月, 张吴琼, 等. 神经梅毒诊断与治疗新进展[J].
中国现代神经疾病杂志,
2016,
16(7): 397-403., articleTitle=神经梅毒诊断与治疗新进展, refAbstract=null), Reference(id=1198684440718311794, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2023, volume=14, issue=1, pageStart=1, pageEnd=11, url=null, language=null, rfNumber=[40], rfOrder=39, authorNames=陆旻雅, 郭佳钰, 张栋, journalName=协和医学杂志, refType=null, unstructuredReference=陆旻雅, 郭佳钰, 张栋, 等. 宏基因组二代测序技术在中枢神经系统感染性疾病中的临床价值分析[J].
协和医学杂志,
2023,
14(1): 1-11., articleTitle=宏基因组二代测序技术在中枢神经系统感染性疾病中的临床价值分析, refAbstract=null), Reference(id=1198684440789614963, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2020, volume=10, issue=null, pageStart=88, pageEnd=null, url=null, language=null, rfNumber=[41], rfOrder=40, authorNames=Xing X, Zhang J, Ma Y, journalName=Front Cellul Infection Microbiol, refType=null, unstructuredReference=
Xing X,
Zhang J,
Ma Y, et al. Metagenomic next-generation sequencing for diagnosis of infectious encephalitis and meningitis: a large, prospective case series of 213 patients[J].
Front Cellul Infection Microbiol,
2020,
10: 88., articleTitle=Metagenomic next-generation sequencing for diagnosis of infectious encephalitis and meningitis: a large, prospective case series of 213 patients, refAbstract=null), Reference(id=1198684440856723828, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2023, volume=23, issue=6, pageStart=479, pageEnd=484, url=null, language=null, rfNumber=[42], rfOrder=41, authorNames=杜倩, 邓素君, 邹姗, journalName=中国现代神经疾病杂志, refType=null, unstructuredReference=杜倩, 邓素君, 邹姗, 等. 宏基因组第二代测序技术在重症中枢神经系统感染中的应用[J].
中国现代神经疾病杂志,
2023,
23(6): 479-484., articleTitle=宏基因组第二代测序技术在重症中枢神经系统感染中的应用, refAbstract=null), Reference(id=1198684440923832693, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2020, volume=18, issue=1, pageStart=199, pageEnd=null, url=null, language=null, rfNumber=[43], rfOrder=42, authorNames=Zhang Y, Cui P, Zhang H, journalName=J Transl Med, refType=null, unstructuredReference=
Zhang Y,
Cui P,
Zhang H, et al. Clinical application and evaluation of metagenomic next-generation sequencing in suspected adult central nervous system infection[J].
J Transl Med,
2020,
18(1): 199., articleTitle=Clinical application and evaluation of metagenomic next-generation sequencing in suspected adult central nervous system infection, refAbstract=null), Reference(id=1198684440986747254, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2020, volume=16, issue=10, pageStart=547, pageEnd=556, url=null, language=null, rfNumber=[44], rfOrder=43, authorNames=Ramachandran PS, Wilson MR, journalName=Nature Reviews Neurol, refType=null, unstructuredReference=
Ramachandran PS,
Wilson MR. Metagenomics for neurological infections - expanding our imagination[J].
Nature Reviews Neurol,
2020,
16(10): 547-556., articleTitle=Metagenomics for neurological infections - expanding our imagination, refAbstract=null), Reference(id=1198684441079021943, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2017, volume=16, issue=11, pageStart=877, pageEnd=897, url=null, language=null, rfNumber=[45], rfOrder=44, authorNames=GBD 2015 Neurological Disorders Collaborator Group, journalName=Lancet Neurol, refType=null, unstructuredReference=GBD 2015 Neurological Disorders Collaborator Group. Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015[J].
Lancet Neurol,
2017,
16(11): 877-897., articleTitle=Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015, refAbstract=null), Reference(id=1198684441137742200, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2017, volume=65, issue=3, pageStart=359, pageEnd=363, url=null, language=null, rfNumber=[46], rfOrder=45, authorNames=Hasbun R, Rosenthal N, Balada-Llasat JM, journalName=Clin Infect Dis, refType=null, unstructuredReference=
Hasbun R,
Rosenthal N,
Balada-Llasat JM, et al. Epidemiology of meningitis and encephalitis in the United States, 2011-2014[J].
Clin Infect Dis,
2017,
65(3): 359-363., articleTitle=Epidemiology of meningitis and encephalitis in the United States, 2011-2014, refAbstract=null), Reference(id=1198684441217433977, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, doi=null, pmid=null, pmcid=null, year=2018, volume=209, issue=10, pageStart=449, pageEnd=454, url=null, language=null, rfNumber=[47], rfOrder=46, authorNames=Beaman MH, journalName=Med J Austral, refType=null, unstructuredReference=
Beaman MH. Community-acquired acute meningitis and encephalitis: a narrative review[J].
Med J Austral,
2018,
209(10): 449-454., articleTitle=Community-acquired acute meningitis and encephalitis: a narrative review, refAbstract=null)], funds=null, companyList=[AuthorCompany(id=1198684432258400514, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, xref=null, ext=[AuthorCompanyExt(id=1198684432266789123, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, companyId=1198684432258400514, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=Department of Neurology, the Second Affiliated Hospital of Army Medical University, Chongqing 400037, China), AuthorCompanyExt(id=1198684432275177732, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, companyId=1198684432258400514, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=陆军军医大学第二附属医院神经内科，重庆 400037)])], figs=[ArticleFig(id=1198684435521569079, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=EN, label=Fig.1, caption=
Annual distribution of 954 cases with infectious diseases of the central nervous system, figureFileSmall=B5meS1Hv/WAx80aq/LrI4g==, figureFileBig=vHonW5nwju40UOdusX7+IA==, tableContent=null), ArticleFig(id=1198684435601260856, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=CN, label=图1, caption=
954例中枢神经系统感染性疾病的年度分布, figureFileSmall=B5meS1Hv/WAx80aq/LrI4g==, figureFileBig=vHonW5nwju40UOdusX7+IA==, tableContent=null), ArticleFig(id=1198684435685146937, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=EN, label=Tab.1, caption=
Annual distribution of 954 cases with infectious diseases of the central nervous system [n(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 2008-2014年 | 2015-2021年 | P |
|---|
| 病毒(n=393) | 73(21.9) | 320(51.6) | <0.001 |
| 结核分枝杆菌(n=361) | 200(59.9) | 161(26.0) |
| 其他细菌(n=108) | 27(8.1) | 81(13.1) |
| 隐球菌(n=75) | 33(9.9) | 42(6.8) |
| 梅毒螺旋体(n=16) | 0 | 16(2.6) |
| 寄生虫(n=1) | 1(0.3) | 0 |
| 合计(n=954) | 334(100.0) | 620(100.0) | |
), ArticleFig(id=1198684435790004538, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=CN, label=表1, caption=
954例中枢神经系统感染性疾病年度分布 [例(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 2008-2014年 | 2015-2021年 | P |
|---|
| 病毒(n=393) | 73(21.9) | 320(51.6) | <0.001 |
| 结核分枝杆菌(n=361) | 200(59.9) | 161(26.0) |
| 其他细菌(n=108) | 27(8.1) | 81(13.1) |
| 隐球菌(n=75) | 33(9.9) | 42(6.8) |
| 梅毒螺旋体(n=16) | 0 | 16(2.6) |
| 寄生虫(n=1) | 1(0.3) | 0 |
| 合计(n=954) | 334(100.0) | 620(100.0) | |
), ArticleFig(id=1198684435886473531, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=EN, label=Tab.2, caption=
Seasonal distribution characteristics of 954 cases with infectious diseases of the central nervous system [n(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 冬季 | 春季 | 夏季 | 秋季 | P |
|---|
| 病毒(n=393) | 91(40.3) | 93(41.7) | 121(43.4) | 88(38.9) | >0.05 |
| 结核分枝杆菌(n=361) | 80(35.4) | 87(39.0) | 99(35.5) | 95(42.0) |
| 其他细菌(n=108) | 30(13.3) | 22(9.9) | 34(12.2) | 22(9.7) |
| 隐球菌(n=75) | 22(9.7) | 15(6.7) | 22(7.9) | 16(7.1) |
| 梅毒螺旋体(n=16) | 3(1.3) | 6(2.7) | 3(1.1) | 4(1.8) |
| 寄生虫(n=1) | 0 | 0 | 0 | 1(0.4) |
| 合计(n=954) | 226(100.0) | 223(100.0) | 279(100.0) | 226(100.0) | |
), ArticleFig(id=1198684435991331132, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=CN, label=表2, caption=
954例中枢神经系统感染性疾病季节分布特征 [例(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 冬季 | 春季 | 夏季 | 秋季 | P |
|---|
| 病毒(n=393) | 91(40.3) | 93(41.7) | 121(43.4) | 88(38.9) | >0.05 |
| 结核分枝杆菌(n=361) | 80(35.4) | 87(39.0) | 99(35.5) | 95(42.0) |
| 其他细菌(n=108) | 30(13.3) | 22(9.9) | 34(12.2) | 22(9.7) |
| 隐球菌(n=75) | 22(9.7) | 15(6.7) | 22(7.9) | 16(7.1) |
| 梅毒螺旋体(n=16) | 3(1.3) | 6(2.7) | 3(1.1) | 4(1.8) |
| 寄生虫(n=1) | 0 | 0 | 0 | 1(0.4) |
| 合计(n=954) | 226(100.0) | 223(100.0) | 279(100.0) | 226(100.0) | |
), ArticleFig(id=1198684436112965949, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=EN, label=Tab.3, caption=
Distribution characteristics of 954 cases with central nervous system infectious diseases in urban and rural areas [n(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 城市 | 农村 | P |
|---|
| 病毒(n=393) | 184(52.9) | 209(34.5)a | <0.001 |
| 结核分枝杆菌(n=361) | 101(29.0) | 260(42.9)a |
| 其他细菌(n=108) | 40(11.5) | 68(11.2) |
| 隐球菌(n=75) | 17(4.9) | 58(9.6)a |
| 梅毒螺旋体(n=16) | 6(1.7) | 10(1.7) |
| 寄生虫(n=1) | 0 | 1(0.2) |
| 合计(n=954) | 348(100.0) | 606(100.0) | |
), ArticleFig(id=1198684436251377982, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=CN, label=表3, caption=
954例中枢神经系统感染性疾病城乡分布特征 [例(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 城市 | 农村 | P |
|---|
| 病毒(n=393) | 184(52.9) | 209(34.5)a | <0.001 |
| 结核分枝杆菌(n=361) | 101(29.0) | 260(42.9)a |
| 其他细菌(n=108) | 40(11.5) | 68(11.2) |
| 隐球菌(n=75) | 17(4.9) | 58(9.6)a |
| 梅毒螺旋体(n=16) | 6(1.7) | 10(1.7) |
| 寄生虫(n=1) | 0 | 1(0.2) |
| 合计(n=954) | 348(100.0) | 606(100.0) | |
), ArticleFig(id=1198684436402372927, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=EN, label=Tab.4, caption=
Sexual distribution characteristics of 954 cases with infectious diseases of the central nervous system [n(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 女性 | 男性 | P |
|---|
| 病毒(n=393) | 151(42.3) | 242(40.5) | <0.05 |
| 结核分枝杆菌(n=361) | 143(40.1) | 218(36.5) |
| 其他细菌(n=108) | 33(9.2) | 75(12.6) |
| 隐球菌(n=75) | 29(8.1) | 46(7.7) |
| 梅毒螺旋体(n=16) | 1(0.3) | 15(2.5) |
| 寄生虫(n=1) | 0 | 1(0.2) |
| 合计(n=954) | 357(100.0) | 597(100.0) | |
), ArticleFig(id=1198684436490453312, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=CN, label=表4, caption=
954例中枢神经系统感染性疾病性别分布特征 [例(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 女性 | 男性 | P |
|---|
| 病毒(n=393) | 151(42.3) | 242(40.5) | <0.05 |
| 结核分枝杆菌(n=361) | 143(40.1) | 218(36.5) |
| 其他细菌(n=108) | 33(9.2) | 75(12.6) |
| 隐球菌(n=75) | 29(8.1) | 46(7.7) |
| 梅毒螺旋体(n=16) | 1(0.3) | 15(2.5) |
| 寄生虫(n=1) | 0 | 1(0.2) |
| 合计(n=954) | 357(100.0) | 597(100.0) | |
), ArticleFig(id=1198684436565950785, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=EN, label=Tab.5, caption=
Age of onset distribution characteristics of 954 cases with infectious diseases of the central nervous system [n(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 14~35岁 | 35~60岁 | >60岁 | χ2 | P |
|---|
| 病毒(n=393) | 164(49.5) | 167(39.7)a | 62(30.7)a | 20.500 | <0.05 |
结核分枝杆菌 (n=361) | 115(34.7) | 153(36.3) | 93(46.0)a |
其他细菌 (n=108) | 34(10.3) | 47(11.2) | 27(13.4) |
| 隐球菌(n=75) | 15(4.5) | 44(10.5) | 16(7.9) |
梅毒螺旋体 (n=16) | 3(0.9) | 9(2.1) | 4(2.0) |
| 寄生虫(n=1) | 0 | 1(0.2) | 0 |
| 合计(n=954) | 331(100.0) | 421(100.0) | 202(100.0) | | |
), ArticleFig(id=1198684436649836866, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=CN, label=表5, caption=
954例中枢神经系统感染性疾病年龄段分布特征 [例(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 14~35岁 | 35~60岁 | >60岁 | χ2 | P |
|---|
| 病毒(n=393) | 164(49.5) | 167(39.7)a | 62(30.7)a | 20.500 | <0.05 |
结核分枝杆菌 (n=361) | 115(34.7) | 153(36.3) | 93(46.0)a |
其他细菌 (n=108) | 34(10.3) | 47(11.2) | 27(13.4) |
| 隐球菌(n=75) | 15(4.5) | 44(10.5) | 16(7.9) |
梅毒螺旋体 (n=16) | 3(0.9) | 9(2.1) | 4(2.0) |
| 寄生虫(n=1) | 0 | 1(0.2) | 0 |
| 合计(n=954) | 331(100.0) | 421(100.0) | 202(100.0) | | |
), ArticleFig(id=1198684436716945731, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=EN, label=Tab.6, caption=
Education level of 639 cases with infectious diseases of the central nervous system
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 初中 及以下 | 高中/
专及以上 | χ2 | P |
|---|
| 病毒(n=325) | 200(45.6) | 125(62.5) | 21.058 | <0.05 |
| 结核分枝杆菌(n=170) | 130(29.6) | 40(20.0) |
| 其他细菌(n=77) | 52(11.8) | 25(12.5) |
| 隐球菌(n=55) | 47(10.7) | 8(4.0) |
| 梅毒螺旋体(n=11) | 9(2.1) | 2(1.0) |
| 寄生虫(n=1) | 1(0.2) | 0 |
| 合计(n=639)* | 439(100.0) | 200(100.0) | | |
), ArticleFig(id=1198684436796637508, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=CN, label=表6, caption=
639例中枢神经系统感染性疾病患者的受教育程度[例(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 初中 及以下 | 高中/
专及以上 | χ2 | P |
|---|
| 病毒(n=325) | 200(45.6) | 125(62.5) | 21.058 | <0.05 |
| 结核分枝杆菌(n=170) | 130(29.6) | 40(20.0) |
| 其他细菌(n=77) | 52(11.8) | 25(12.5) |
| 隐球菌(n=55) | 47(10.7) | 8(4.0) |
| 梅毒螺旋体(n=11) | 9(2.1) | 2(1.0) |
| 寄生虫(n=1) | 1(0.2) | 0 |
| 合计(n=639)* | 439(100.0) | 200(100.0) | | |
), ArticleFig(id=1198684436867940677, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=EN, label=Tab.7, caption=
Occupation distribution of 628 cases with infectious diseases of the central nervous system [n(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 农民 | 工人 | 公务员/专业技术人员 | 商务/服务人员 | 学生 | P |
|---|
| 合计(n=628) | 286(100.0) | 142(100.0) | 64(100.0) | 47(100.0) | 89(100.0) | |
| 病毒(n=295) | 100(35.0) | 73(51.4)a | 36(56.3)a | 30(63.8)a | 56(62.9)a | |
| 结核分枝杆菌(n=189) | 110(38.5) | 36(25.4) | 8(12.5)a | 11(23.4) | 24(27.0) | |
| 其他细菌(n=78) | 34(11.9) | 19(13.4) | 13(20.3) | 3(6.4) | 9(10.1) | <0.001 |
| 隐球菌(n=55) | 33(11.5)b | 13(9.2)b | 6(9.4)b | 3(6.4) | 0a | |
| 梅毒螺旋体(n=10) | 8(2.8) | 1(0.7) | 1(1.6) | 0 | 0 | |
| 寄生虫(n=1) | 1(0.3) | 0 | 0 | 0 | 0 | |
), ArticleFig(id=1198684436981186886, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=CN, label=表7, caption=
628例中枢神经系统感染性疾病职业分布 [例(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 农民 | 工人 | 公务员/专业技术人员 | 商务/服务人员 | 学生 | P |
|---|
| 合计(n=628) | 286(100.0) | 142(100.0) | 64(100.0) | 47(100.0) | 89(100.0) | |
| 病毒(n=295) | 100(35.0) | 73(51.4)a | 36(56.3)a | 30(63.8)a | 56(62.9)a | |
| 结核分枝杆菌(n=189) | 110(38.5) | 36(25.4) | 8(12.5)a | 11(23.4) | 24(27.0) | |
| 其他细菌(n=78) | 34(11.9) | 19(13.4) | 13(20.3) | 3(6.4) | 9(10.1) | <0.001 |
| 隐球菌(n=55) | 33(11.5)b | 13(9.2)b | 6(9.4)b | 3(6.4) | 0a | |
| 梅毒螺旋体(n=10) | 8(2.8) | 1(0.7) | 1(1.6) | 0 | 0 | |
| 寄生虫(n=1) | 1(0.3) | 0 | 0 | 0 | 0 | |
), ArticleFig(id=1198684437086044487, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=EN, label=Tab.8, caption=
Clinical manifestations of 954 cases with infectious diseases of the central nervous system [n(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 发热 | 头痛 | 恶心呕吐 | 脑膜 刺激征 | 病理征 阳性 | 意识 障碍 | 精神行 为异常 | 认知功 能下降 | 癫痫 | 颅神经 受损 | 肢体 无力 | 感觉 障碍 | 共济 失调 | 自主神经功能 |
|---|
| 合计(n=964) | 559(58.6) | 742(77.8) | 322(33.8) | 323(33.9) | 43(4.5) | 119(12.5) | 113(11.8) | 50(5.2) | 47(4.9) | 34(3.6) | 68(7.1) | 17(1.8) | 13(1.4) | 25(2.6) |
| 病毒(n=393) | 224(57.0) | 291(74.0 ) | 109(27.7) | 100(25.4) | 6(1.5) | 35(8.9) | 61(15.5) | 27(6.9) | 29(7.4) | 17(4.3) | 15(3.8) | 0 | 4(1.0) | 8(2.0) |
结核分枝杆菌 (n=361) | 219(60.7) | 289(80.1) | 131(36.3) | 144(39.9) | 25(6.9) | 59(16.3) | 38(10.5) | 8(2.2) | 12(3.3) | 11(3.0) | 39(10.8) | 13(3.6) | 9(2.5) | 10(2.8) |
其他细菌 (n=108) | 80(74.1) | 93(86.1) | 42(38.9) | 46(42.6) | 5(4.6) | 15(13.9) | 6(5.6) | 3(2.8) | 3(2.8) | 1(0.9) | 7(6.5) | 3(2.8) | 0 | 4(3.7) |
| 隐球菌(n=75) | 35(46.7) | 67(89.3) | 39(52.0) | 32(42.7) | 6(8.0) | 9(12.0) | 4(5.3) | 3(4.0) | 1(1.3) | 4(5.3) | 5(6.7) | 0 | 0 | 2(2.7) |
梅毒螺旋体 (n=16) | 0 | 1(6.3) | 0 | 0 | 0 | 0 | 3(18.8) | 9(56.3) | 1(6.3) | 1(6.3) | 2(12.5) | 1(6.3) | 0 | 1(6.3) |
| 寄生虫(n=1) | 1(100.0) | 1(100.0) | 1(100.0) | 1(100.0) | 1(100.0) | 1(100.0) | 1(100.0) | 0 | 1(100.0) | 0 | 0 | 0 | 0 | 0 |
), ArticleFig(id=1198684437182513480, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=CN, label=表8, caption=
954例中枢神经系统感染性疾病的临床表现 [例(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 发热 | 头痛 | 恶心呕吐 | 脑膜 刺激征 | 病理征 阳性 | 意识 障碍 | 精神行 为异常 | 认知功 能下降 | 癫痫 | 颅神经 受损 | 肢体 无力 | 感觉 障碍 | 共济 失调 | 自主神经功能 |
|---|
| 合计(n=964) | 559(58.6) | 742(77.8) | 322(33.8) | 323(33.9) | 43(4.5) | 119(12.5) | 113(11.8) | 50(5.2) | 47(4.9) | 34(3.6) | 68(7.1) | 17(1.8) | 13(1.4) | 25(2.6) |
| 病毒(n=393) | 224(57.0) | 291(74.0 ) | 109(27.7) | 100(25.4) | 6(1.5) | 35(8.9) | 61(15.5) | 27(6.9) | 29(7.4) | 17(4.3) | 15(3.8) | 0 | 4(1.0) | 8(2.0) |
结核分枝杆菌 (n=361) | 219(60.7) | 289(80.1) | 131(36.3) | 144(39.9) | 25(6.9) | 59(16.3) | 38(10.5) | 8(2.2) | 12(3.3) | 11(3.0) | 39(10.8) | 13(3.6) | 9(2.5) | 10(2.8) |
其他细菌 (n=108) | 80(74.1) | 93(86.1) | 42(38.9) | 46(42.6) | 5(4.6) | 15(13.9) | 6(5.6) | 3(2.8) | 3(2.8) | 1(0.9) | 7(6.5) | 3(2.8) | 0 | 4(3.7) |
| 隐球菌(n=75) | 35(46.7) | 67(89.3) | 39(52.0) | 32(42.7) | 6(8.0) | 9(12.0) | 4(5.3) | 3(4.0) | 1(1.3) | 4(5.3) | 5(6.7) | 0 | 0 | 2(2.7) |
梅毒螺旋体 (n=16) | 0 | 1(6.3) | 0 | 0 | 0 | 0 | 3(18.8) | 9(56.3) | 1(6.3) | 1(6.3) | 2(12.5) | 1(6.3) | 0 | 1(6.3) |
| 寄生虫(n=1) | 1(100.0) | 1(100.0) | 1(100.0) | 1(100.0) | 1(100.0) | 1(100.0) | 1(100.0) | 0 | 1(100.0) | 0 | 0 | 0 | 0 | 0 |
), ArticleFig(id=1198684437262205257, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=EN, label=Tab.9, caption=
Prognosis of 850 cases with infectious diseases of the central nervous system [n(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 预后良好 | 预后不良 | P |
|---|
| 病毒(n=326) | 323(99.1) | 3(0.9) | <0.05 |
| 结核分枝杆菌(n=328) | 315(96.0) | 13(4.0) |
| 其他细菌(n=107) | 106(99.1) | 1(0.9) |
| 隐球菌(n=72) | 69(95.8) | 3(4.2) |
| 梅毒螺旋体(n=16) | 16(100.0) | 0 |
| 寄生虫(n=1) | 0 | 1(100.0) |
| 合计(n=850) | 829(97.5) | 21(2.5) | |
), ArticleFig(id=1198684437329314122, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1198623859374125874, language=CN, label=表9, caption=
850例中枢神经系统感染性疾病预后 [例(%)]
, figureFileSmall=null, figureFileBig=null, tableContent=
| 病原体 | 预后良好 | 预后不良 | P |
|---|
| 病毒(n=326) | 323(99.1) | 3(0.9) | <0.05 |
| 结核分枝杆菌(n=328) | 315(96.0) | 13(4.0) |
| 其他细菌(n=107) | 106(99.1) | 1(0.9) |
| 隐球菌(n=72) | 69(95.8) | 3(4.2) |
| 梅毒螺旋体(n=16) | 16(100.0) | 0 |
| 寄生虫(n=1) | 0 | 1(100.0) |
| 合计(n=850) | 829(97.5) | 21(2.5) | |
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