Article(id=1198558109527540673, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1198558106218230069, articleNumber=null, orderNo=null, doi=10.11855/j.issn.0577-7402.1066.2024.0514, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=research-article, receivedDate=1693065600000, receivedDateStr=2023-08-27, revisedDate=null, revisedDateStr=null, acceptedDate=1696608000000, acceptedDateStr=2023-10-07, onlineDate=1763688121443, onlineDateStr=2025-11-21, pubDate=1727452800000, pubDateStr=2024-09-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1763688121443, onlineIssueDateStr=2025-11-21, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1763688121443, creator=13701087609, updateTime=1763688121443, updator=13701087609, issue=Issue{id=1198558106218230069, tenantId=1146029695717560320, journalId=1189873630562394117, year='2024', volume='49', issue='9', pageStart='977', pageEnd='1098', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1763688120655, creator=13701087609, updateTime=1763689155065, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1198562444915339352, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1198558106218230069, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1198562444915339353, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1198558106218230069, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=1088, endPage=1093, ext={EN=ArticleExt(id=1198558110903272389, articleId=1198558109527540673, tenantId=1146029695717560320, journalId=1189873630562394117, language=EN, title=Research progress on the impact of lipid metabolism on endometrial receptivity and embryo implantation, columnId=1190243275882729994, journalTitle=Medical Journal of Chinese People’s Liberation Army, columnName=Review, runingTitle=null, highlight=null, articleAbstract=

Lipids, including fats (triglycerides) and lipoids (phospholipids and sterols), not only serve as an energy source for the body but also play a pivotal role throughout the reproductive process, particularly in the establishment and maintenance of early pregnancy. This encompasses the regulate of early embryonic development and uterine tolerance, and the facilitation of embryo implantation. Given the diversity of lipids, this review focuses on extensively studied lipid mediators such as polyunsaturated fatty acids, endocannabinoids, prostaglandins, lysophosphatidic acid, sphingolipids and steroid hormones. It systematically elaborates on the regulatory effects of fatty acid, phospholipid, and cholesterol metabolism on the formation of endometrial receptivity and embryo implantation, as well as the potential underlying mechanisms. The review aims to provide new insights and feasible intervention approaches for predicting and improving the outcomes of natural pregnancy and/or assisted reproductive technology.

, correspAuthors=Duo-Jia Zhang, authorNote=null, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, authorCompany=null, fund=null, authors=null, authorsList=Li-Na Ma, Ying Qin, Ke-Hua Wang, Cong-Hui Pang, Li-Ge Lu, Wen-Xian Yuan, Duo-Jia Zhang, Xiao-Ke Wu), CN=ArticleExt(id=1198558111301731279, articleId=1198558109527540673, tenantId=1146029695717560320, journalId=1189873630562394117, language=CN, title=脂质代谢对子宫内膜容受性及胚胎着床影响的研究进展, columnId=1190243276029530637, journalTitle=解放军医学杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

脂类包括脂肪(三酰甘油)及类脂(磷脂、固醇类)，除为机体提供能量外，脂质代谢也在整个生殖过程中发挥重要作用，尤其是早期妊娠的建立和维持(包括调节早期胚胎的发育和子宫的容受性，以及促进胚胎的着床)阶段。鉴于脂质种类繁多，本文着重从多不饱和脂肪酸、内源性大麻素、前列腺素、溶血磷脂酸、鞘磷脂、类固醇激素等被广泛研究的脂质介质，系统阐述脂肪酸、磷脂、胆固醇代谢对子宫内膜容受性形成及胚胎着床的调控作用，以及可能的潜在机制，以期为预测和改善自然妊娠和(或)辅助生殖助孕的结局提供新的切入点及可行的干预途径。

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马丽娜，医学博士，主要从事妇产科生殖内分泌等方面的研究

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