Article(id=1190669166370762988, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1190669163988398295, articleNumber=null, orderNo=null, doi=10.11855/j.issn.0577-7402.1671.2024.0704, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=research-article, receivedDate=1702828800000, receivedDateStr=2023-12-18, revisedDate=null, revisedDateStr=null, acceptedDate=1706112000000, acceptedDateStr=2024-01-25, onlineDate=1761807250825, onlineDateStr=2025-10-30, pubDate=1745769600000, pubDateStr=2025-04-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1761807250825, onlineIssueDateStr=2025-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1761807250825, creator=13701087609, updateTime=1761807250825, updator=13701087609, issue=Issue{id=1190669163988398295, tenantId=1146029695717560320, journalId=1189873630562394117, year='2025', volume='50', issue='4', pageStart='367', pageEnd='503', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1761807250258, creator=13701087609, updateTime=1761807667423, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1190670913772339410, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1190669163988398295, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1190670913772339411, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1190669163988398295, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=490, endPage=494, ext={EN=ArticleExt(id=1190669166614032622, articleId=1190669166370762988, tenantId=1146029695717560320, journalId=1189873630562394117, language=EN, title=Research progress on the role of neurovascular unit dysfunction in elderly patients with epileptic seizures, columnId=1190243275882729994, journalTitle=Medical Journal of Chinese People’s Liberation Army, columnName=Review, runingTitle=null, highlight=null, articleAbstract=

The neurovascular unit (NVU) is the smallest structural unit that maintains the integrity of the blood-brain barrier (BBB), regulates cerebral physiological activities, and maintains the homeostasis of the brain's internal environment. It has become a hot topic in the study of brain physiology and pathological changes. NVU plays a crucial role in age-dependent central nervous system diseases such as cerebral white matter lesions, cognitive impairment, and cerebrovascular disease. Its dysfunction can lead to destruction of BBB integrity, with subsequent protein leakage, immune-inflammatory responses, and alterations in cerebral hemodynamics, all of which can trigger seizures or progression of neurodegenerative disorders. Conversely, seizures can also accelerate NVU dysfunction and promote brain aging. The review summarizes the role of dysfunctional constituent cells of the NVU in the pathogenesis of age-dependent epilepsy and the research progress in related molecular pathways, aiming to provide new perspectives for epilepsy treatment research.

, correspAuthors=Rong Yin, authorNote=null, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, authorCompany=null, fund=null, authors=null, authorsList=Xuan Liu, Rong Yin), CN=ArticleExt(id=1190669204685730052, articleId=1190669166370762988, tenantId=1146029695717560320, journalId=1189873630562394117, language=CN, title=老年癫痫发作中神经血管单元功能障碍的作用机制研究进展, columnId=1190243276029530637, journalTitle=解放军医学杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

神经血管单元(NVU)是维持血脑屏障(BBB)完整性、调节大脑生理活动、维持大脑内环境稳态的最小结构单元，已成为大脑生理活动及病理变化研究的热点领域。NVU在脑白质病变、认知障碍、脑血管疾病等年龄依赖性中枢神经系统疾病中具有重要作用，其功能障碍会导致BBB完整性破坏，随之而来的蛋白质渗漏、免疫炎症反应、脑血流动力学改变均可导致癫痫发作或神经退行性疾病进展；反之，癫痫发作亦可加速NVU功能障碍而促进脑衰老。本文综述NVU的组成细胞功能障碍在年龄依赖性癫痫发病过程中的作用机制及相关分子通路的研究进展，旨在为癫痫治疗研究提供新的思路。

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刘璇，硕士研究生，主要从事癫痫、脑血管病的相关研究

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刘璇，硕士研究生，主要从事癫痫、脑血管病的相关研究

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Sci, refType=null, unstructuredReference=Yamanaka G, Morichi S, Takamatsu T, et al. Links between immune cells from the periphery and the brain in the pathogenesis of epilepsy: a narrative review[J]. Int J Mol Sci, 2021, 22(9): 4395., articleTitle=Links between immune cells from the periphery and the brain in the pathogenesis of epilepsy: a narrative review, refAbstract=null), Reference(id=1190669207151980837, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2020, volume=395, issue=10225, pageStart=735, pageEnd=748, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=Sen A, Jette N, Husain M, journalName=Lancet, refType=null, unstructuredReference=Sen A, Jette N, Husain M, et al. Epilepsy in older people[J]. Lancet, 2020, 395(10225): 735-748., articleTitle=Epilepsy in older people, refAbstract=null), Reference(id=1190669207256838438, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2006, volume=68, issue=null, pageStart=S39, pageEnd=S48, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=Cloyd J, Hauser W, Towne A, journalName=Epilepsy Res, refType=null, unstructuredReference=Cloyd J, Hauser W, Towne A, et al. Epidemiological and medical aspects of epilepsy in the elderly[J]. Epilepsy Res, 2006, 68(Suppl 1): S39-S48., articleTitle=Epidemiological and medical aspects of epilepsy in the elderly, refAbstract=null), Reference(id=1190669207500108071, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2024, volume=49, issue=8, pageStart=868, pageEnd=875, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=毛丹丹, 刘平, 胡文广, journalName=解放军医学杂志, refType=null, unstructuredReference=毛丹丹, 刘平, 胡文广, 等. 促肾上腺皮质激素治疗婴儿癫痫性痉挛综合征疗效的影响因素及其预测指标[J]. 解放军医学杂志, 2024, 49(8): 868-875., articleTitle=促肾上腺皮质激素治疗婴儿癫痫性痉挛综合征疗效的影响因素及其预测指标, refAbstract=null), Reference(id=1190669207563022632, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2021, volume=9, issue=7, pageStart=759, pageEnd=null, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=Yamanaka G, Takata F, Kataoka Y, journalName=Biomedicines, refType=null, unstructuredReference=Yamanaka G, Takata F, Kataoka Y, et al. The neuroinflammatory role of pericytes in epilepsy[J]. Biomedicines, 2021, 9(7): 759., articleTitle=The neuroinflammatory role of pericytes in epilepsy, refAbstract=null), Reference(id=1190669207638520105, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2020, volume=9, issue=12, pageStart=2650, pageEnd=null, url=null, language=null, rfNumber=[6], rfOrder=5, authorNames=Nishibori M, Wang D, Ousaka D, journalName=Cells, refType=null, unstructuredReference=Nishibori M, Wang D, Ousaka D, et al. High mobility group Box-1 and blood-brain barrier disruption[J]. Cells, 2020, 9(12): 2650., articleTitle=High mobility group Box-1 and blood-brain barrier disruption, refAbstract=null), Reference(id=1190669207747572010, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2020, volume=21, issue=2, pageStart=591, pageEnd=null, url=null, language=null, rfNumber=[7], rfOrder=6, authorNames=Löscher W, Friedman A, journalName=Int J Mol Sci, refType=null, unstructuredReference=Löscher W, Friedman A. Structural, molecular, and functional alterations of the blood-brain barrier during epileptogenesis and epilepsy: a cause, consequence, or both?[J]. Int J Mol Sci, 2020, 21(2): 591., articleTitle=Structural, molecular, and functional alterations of the blood-brain barrier during epileptogenesis and epilepsy: a cause, consequence, or both?, refAbstract=null), Reference(id=1190669207827263787, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2023, volume=33, issue=2, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[8], rfOrder=7, authorNames=Reiss Y, Bauer S, David B, journalName=Brain Pathol, refType=null, unstructuredReference=Reiss Y, Bauer S, David B, et al. The neurovasculature as a target in temporal lobe epilepsy[J]. Brain Pathol, 2023, 33(2): e13147., articleTitle=The neurovasculature as a target in temporal lobe epilepsy, refAbstract=null), Reference(id=1190669207894372652, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2015, volume=163, issue=5, pageStart=1064, pageEnd=1078, url=null, language=null, rfNumber=[9], rfOrder=8, authorNames=Zhao Z, Nelson AR, Betsholtz C, journalName=Cell, refType=null, unstructuredReference=Zhao Z, Nelson AR, Betsholtz C, et al. Establishment and dysfunction of the blood-brain barrier[J]. Cell, 2015, 163(5): 1064-1078., articleTitle=Establishment and dysfunction of the blood-brain barrier, refAbstract=null), Reference(id=1190669208976503085, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2010, volume=37, issue=1, pageStart=13, pageEnd=25, url=null, language=null, rfNumber=[10], rfOrder=9, authorNames=Abbott NJ, Patabendige AA, Dolman DE, journalName=Neurobiol Dis, refType=null, unstructuredReference=Abbott NJ, Patabendige AA, Dolman DE, et al. Structure and function of the blood-brain barrier[J]. Neurobiol Dis, 2010, 37(1): 13-25., articleTitle=Structure and function of the blood-brain barrier, refAbstract=null), Reference(id=1190669209031029038, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2022, volume=63, issue=6, pageStart=1297, pageEnd=1313, url=null, language=null, rfNumber=[11], rfOrder=10, authorNames=van Vliet EA, Marchi N, journalName=Epilepsia, refType=null, unstructuredReference=van Vliet EA, Marchi N. Neurovascular unit dysfunction as a mechanism of seizures and epilepsy during aging[J]. Epilepsia, 2022, 63(6): 1297-1313., articleTitle=Neurovascular unit dysfunction as a mechanism of seizures and epilepsy during aging, refAbstract=null), Reference(id=1190669209089749295, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2020, volume=42, issue=4, pageStart=1183, pageEnd=1193, url=null, language=null, rfNumber=[12], rfOrder=11, authorNames=Verheggen ICM, de Jong JJA, van Boxtel MPJ, journalName=Geroscience, refType=null, unstructuredReference=Verheggen ICM, de Jong JJA, van Boxtel MPJ, et al. Increase in blood-brain barrier leakage in healthy, older adults[J]. Geroscience, 2020, 42(4): 1183-1193., articleTitle=Increase in blood-brain barrier leakage in healthy, older adults, refAbstract=null), Reference(id=1190669209215578416, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2022, volume=19, issue=1, pageStart=29, pageEnd=null, url=null, language=null, rfNumber=[13], rfOrder=12, authorNames=Huang WY, Lai YL, Liu KH, journalName=J Neuroinflammation, refType=null, unstructuredReference=Huang WY, Lai YL, Liu KH, et al. TNFα-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation[J]. J Neuroinflammation, 2022, 19(1): 29., articleTitle=TNFα-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation, refAbstract=null), Reference(id=1190669209370767665, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2019, volume=10, issue=null, pageStart=1583, pageEnd=null, url=null, language=null, rfNumber=[14], rfOrder=13, authorNames=Baruah J, Vasudevan A, Köhling R, journalName=Front Physiol, refType=null, unstructuredReference=Baruah J, Vasudevan A, Köhling R. Vascular integrity and signaling determining brain development, network excitability, and epileptogenesis[J]. Front Physiol, 2019, 10: 1583., articleTitle=Vascular integrity and signaling determining brain development, network excitability, and epileptogenesis, refAbstract=null), Reference(id=1190669209429487922, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2021, volume=1758, issue=null, pageStart=147343, pageEnd=null, url=null, language=null, rfNumber=[15], rfOrder=14, authorNames=Sarahian N, Mohammadi MT, Darabi S, journalName=Brain Res, refType=null, unstructuredReference=Sarahian N, Mohammadi MT, Darabi S, et al. Fenofibrate protects the neurovascular unit and ameliorates plasma corticosterone levels in pentylenetetrazole-induced kindling seizure in mice[J]. Brain Res, 2021, 1758: 147343., articleTitle=Fenofibrate protects the neurovascular unit and ameliorates plasma corticosterone levels in pentylenetetrazole-induced kindling seizure in mice, refAbstract=null), Reference(id=1190669209484013875, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2016, volume=113, issue=38, pageStart=E5665, pageEnd=E5674, url=null, language=null, rfNumber=[16], rfOrder=15, authorNames=Varvel NH, Neher JJ, Bosch A, journalName=Proc Natl Acad Sci U S A, refType=null, unstructuredReference=Varvel NH, Neher JJ, Bosch A, et al. Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus[J]. Proc Natl Acad Sci U S A, 2016, 113(38): E5665-E5674., articleTitle=Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus, refAbstract=null), Reference(id=1190669209605648692, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2017, volume=37, issue=33, pageStart=7878, pageEnd=7892, url=null, language=null, rfNumber=[17], rfOrder=16, authorNames=Tian DS, Peng J, Murugan M, journalName=J Neurosci, refType=null, unstructuredReference=Tian DS, Peng J, Murugan M, et al. Chemokine CCL2-CCR2 signaling induces neuronal cell death via STAT3 activation and IL-1β production after status epilepticus[J]. J Neurosci, 2017, 37(33): 7878-7892., articleTitle=Chemokine CCL2-CCR2 signaling induces neuronal cell death via STAT3 activation and IL-1β production after status epilepticus, refAbstract=null), Reference(id=1190669209727283509, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2019, volume=15, issue=8, pageStart=459, pageEnd=472, url=null, language=null, rfNumber=[18], rfOrder=17, authorNames=Vezzani A, Balosso S, Ravizza T, journalName=Nat Rev Neurol, refType=null, unstructuredReference=Vezzani A, Balosso S, Ravizza T. Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy[J]. Nat Rev Neurol, 2019, 15(8): 459-472., articleTitle=Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy, refAbstract=null), Reference(id=1190669209786003766, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2022, volume=13, issue=1, pageStart=2003, pageEnd=null, url=null, language=null, rfNumber=[19], rfOrder=18, authorNames=Greene C, Hanley N, Reschke CR, journalName=Nat Commun, refType=null, unstructuredReference=Greene C, Hanley N, Reschke CR, et al. Microvascular stabilization via blood-brain barrier regulation prevents seizure activity[J]. Nat Commun, 2022, 13(1): 2003., articleTitle=Microvascular stabilization via blood-brain barrier regulation prevents seizure activity, refAbstract=null), Reference(id=1190669209848918327, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2018, volume=141, issue=10, pageStart=2952, pageEnd=2965, url=null, language=null, rfNumber=[20], rfOrder=19, authorNames=Rüber T, David B, Lüchters G, journalName=Brain, refType=null, unstructuredReference=Rüber T, David B, Lüchters G, et al. Evidence for peri-ictal blood-brain barrier dysfunction in patients with epilepsy[J]. Brain, 2018, 141(10): 2952-2965., articleTitle=Evidence for peri-ictal blood-brain barrier dysfunction in patients with epilepsy, refAbstract=null), Reference(id=1190669209916027192, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2020, volume=217, issue=1, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[21], rfOrder=20, authorNames=Liu XX, Yang L, Shao LX, journalName=J Exp Med, refType=null, unstructuredReference=Liu XX, Yang L, Shao LX, et al. Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis[J]. J Exp Med, 2020, 217(1): e20180992., articleTitle=Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis, refAbstract=null), Reference(id=1190669209974747449, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2007, volume=55, issue=3, pageStart=274, pageEnd=281, url=null, language=null, rfNumber=[22], rfOrder=21, authorNames=Kucheryavykh YV, Kucheryavykh LY, Nichols CG, journalName=Glia, refType=null, unstructuredReference=Kucheryavykh YV, Kucheryavykh LY, Nichols CG, et al. Downregulation of Kir4.1 inward rectifying potassium channel subunits by RNAi impairs potassium transfer and glutamate uptake by cultured cortical astrocytes[J]. Glia, 2007, 55(3): 274-281., articleTitle=Downregulation of Kir4.1 inward rectifying potassium channel subunits by RNAi impairs potassium transfer and glutamate uptake by cultured cortical astrocytes, refAbstract=null), Reference(id=1190669210029273402, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2016, volume=26, issue=4, pageStart=249, pageEnd=261, url=null, language=null, rfNumber=[23], rfOrder=22, authorNames=Blaser H, Dostert C, Mak TW, journalName=Trends Cell Biol, refType=null, unstructuredReference=Blaser H, Dostert C, Mak TW, et al. TNF and ROS crosstalk in inflammation[J]. Trends Cell Biol, 2016, 26(4): 249-261., articleTitle=TNF and ROS crosstalk in inflammation, refAbstract=null), Reference(id=1190669210087993659, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2016, volume=1862, issue=3, pageStart=472, pageEnd=482, url=null, language=null, rfNumber=[24], rfOrder=23, authorNames=Lécuyer MA, Kebir H, Prat A, journalName=Biochim Biophys Acta, refType=null, unstructuredReference=Lécuyer MA, Kebir H, Prat A. Glial influences on BBB functions and molecular players in immune cell trafficking[J]. Biochim Biophys Acta, 2016, 1862(3): 472-482., articleTitle=Glial influences on BBB functions and molecular players in immune cell trafficking, refAbstract=null), Reference(id=1190669210163491132, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2019, volume=123, issue=null, pageStart=20, pageEnd=26, url=null, language=null, rfNumber=[25], rfOrder=24, authorNames=Dadas A, Janigro D, journalName=Neurobiol Dis, refType=null, unstructuredReference=Dadas A, Janigro D. Breakdown of blood brain barrier as a mechanism of post-traumatic epilepsy[J]. Neurobiol Dis, 2019, 123: 20-26., articleTitle=Breakdown of blood brain barrier as a mechanism of post-traumatic epilepsy, refAbstract=null), Reference(id=1190669210230599997, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2017, volume=231, issue=3, pageStart=366, pageEnd=379, url=null, language=null, rfNumber=[26], rfOrder=25, authorNames=Setkowicz Z, Kosonowska E, Janeczko K, journalName=J Anat, refType=null, unstructuredReference=Setkowicz Z, Kosonowska E, Janeczko K. Inflammation in the developing rat modulates astroglial reactivity to seizures in the mature brain[J]. J Anat, 2017, 231(3): 366-379., articleTitle=Inflammation in the developing rat modulates astroglial reactivity to seizures in the mature brain, refAbstract=null), Reference(id=1190669210339651902, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2021, volume=69, issue=11, pageStart=2618, pageEnd=2643, url=null, language=null, rfNumber=[27], rfOrder=26, authorNames=Kyriatzis G, Bernard A, Bôle A, journalName=Glia, refType=null, unstructuredReference=Kyriatzis G, Bernard A, Bôle A, et al. Neurotensin receptor 2 is induced in astrocytes and brain endothelial cells in relation to neuroinflammation following pilocarpine-induced seizures in rats[J]. Glia, 2021, 69(11): 2618-2643., articleTitle=Neurotensin receptor 2 is induced in astrocytes and brain endothelial cells in relation to neuroinflammation following pilocarpine-induced seizures in rats, refAbstract=null), Reference(id=1190669210398372159, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2019, volume=67, issue=8, pageStart=1434, pageEnd=1448, url=null, language=null, rfNumber=[28], rfOrder=27, authorNames=Feng L, Murugan M, Bosco DB, journalName=Glia, refType=null, unstructuredReference=Feng L, Murugan M, Bosco DB, et al. Microglial proliferation and monocyte infiltration contribute to microgliosis following status epilepticus[J]. Glia, 2019, 67(8): 1434-1448., articleTitle=Microglial proliferation and monocyte infiltration contribute to microgliosis following status epilepticus, refAbstract=null), Reference(id=1190669210540978496, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2018, volume=11, issue=1, pageStart=34, pageEnd=null, url=null, language=null, rfNumber=[29], rfOrder=28, authorNames=Bosco DB, Zheng J, Xu Z, journalName=Mol Brain, refType=null, unstructuredReference=Bosco DB, Zheng J, Xu Z, et al. RNA-seq analysis of hippocampal microglia after kainic acid-induced seizures[J]. Mol Brain, 2018, 11(1): 34., articleTitle=RNA-seq analysis of hippocampal microglia after kainic acid-induced seizures, refAbstract=null), Reference(id=1190669210641641793, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2010, volume=285, issue=50, pageStart=39447, pageEnd=39457, url=null, language=null, rfNumber=[30], rfOrder=29, authorNames=Hong J, Cho IH, Kwak KI, journalName=J Biol Chem, refType=null, unstructuredReference=Hong J, Cho IH, Kwak KI, et al. Microglial Toll-like receptor 2 contributes to kainic acid-induced glial activation and hippocampal neuronal cell death[J]. J Biol Chem, 2010, 285(50): 39447-39457., articleTitle=Microglial Toll-like receptor 2 contributes to kainic acid-induced glial activation and hippocampal neuronal cell death, refAbstract=null), Reference(id=1190669210717139266, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2009, volume=4, issue=8, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[31], rfOrder=30, authorNames=Menteyne A, Levavasseur F, Audinat E, journalName=PLoS One, refType=null, unstructuredReference=Menteyne A, Levavasseur F, Audinat E, et al. Predominant functional expression of Kv1.3 by activated microglia of the hippocampus after Status epilepticus[J]. PLoS One, 2009, 4(8): e6770., articleTitle=Predominant functional expression of Kv1.3 by activated microglia of the hippocampus after Status epilepticus, refAbstract=null), Reference(id=1190669210788442435, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2015, volume=44, issue=3, pageStart=797, pageEnd=808, url=null, language=null, rfNumber=[32], rfOrder=31, authorNames=Rangaraju S, Gearing M, Jin LW, journalName=J Alzheimers Dis, refType=null, unstructuredReference=Rangaraju S, Gearing M, Jin LW, et al. Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease[J]. J Alzheimers Dis, 2015, 44(3): 797-808., articleTitle=Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease, refAbstract=null), Reference(id=1190669210947825988, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2014, volume=82, issue=2, pageStart=380, pageEnd=397, url=null, language=null, rfNumber=[33], rfOrder=32, authorNames=Elmore MR, Najafi AR, Koike MA, journalName=Neuron, refType=null, unstructuredReference=Elmore MR, Najafi AR, Koike MA, et al. Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain[J]. Neuron, 2014, 82(2): 380-397., articleTitle=Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain, refAbstract=null), Reference(id=1190669211002351941, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2007, volume=48, issue=4, pageStart=732, pageEnd=742, url=null, language=null, rfNumber=[34], rfOrder=33, authorNames=Marchi N, Angelov L, Masaryk T, journalName=Epilepsia, refType=null, unstructuredReference=Marchi N, Angelov L, Masaryk T, et al. Seizure-promoting effect of blood-brain barrier disruption[J]. Epilepsia, 2007, 48(4): 732-742., articleTitle=Seizure-promoting effect of blood-brain barrier disruption, refAbstract=null), Reference(id=1190669211082043718, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2021, volume=44, issue=5, pageStart=487, pageEnd=498, url=null, language=null, rfNumber=[35], rfOrder=34, authorNames=Uprety A, Kang Y, Kim SY, journalName=Arch Pharm Res, refType=null, unstructuredReference=Uprety A, Kang Y, Kim SY. Blood-brain barrier dysfunction as a potential therapeutic target for neurodegenerative disorders[J]. Arch Pharm Res, 2021, 44(5): 487-498., articleTitle=Blood-brain barrier dysfunction as a potential therapeutic target for neurodegenerative disorders, refAbstract=null), Reference(id=1190669211165929799, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2019, volume=60, issue=2, pageStart=322, pageEnd=336, url=null, language=null, rfNumber=[36], rfOrder=35, authorNames=Prager O, Kamintsky L, Hasam-Henderson LA, journalName=Epilepsia, refType=null, unstructuredReference=Prager O, Kamintsky L, Hasam-Henderson LA, et al. Seizure-induced microvascular injury is associated with impaired neurovascular coupling and blood-brain barrier dysfunction[J]. Epilepsia, 2019, 60(2): 322-336., articleTitle=Seizure-induced microvascular injury is associated with impaired neurovascular coupling and blood-brain barrier dysfunction, refAbstract=null), Reference(id=1190669211300147528, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2019, volume=99, issue=1, pageStart=21, pageEnd=78, url=null, language=null, rfNumber=[37], rfOrder=36, authorNames=Sweeney MD, Zhao Z, Montagne A, journalName=Physiol Rev, refType=null, unstructuredReference=Sweeney MD, Zhao Z, Montagne A, et al. Blood-brain barrier: from physiology to disease and back[J]. Physiol Rev, 2019, 99(1): 21-78., articleTitle=Blood-brain barrier: from physiology to disease and back, refAbstract=null), Reference(id=1190669211417588041, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2019, volume=60, issue=7, pageStart=1399, pageEnd=1411, url=null, language=null, rfNumber=[38], rfOrder=37, authorNames=Klement W, Blaquiere M, Zub E, journalName=Epilepsia, refType=null, unstructuredReference=Klement W, Blaquiere M, Zub E, et al. A pericyte-glia scarring develops at the leaky capillaries in the hippocampus during seizure activity[J]. Epilepsia, 2019, 60(7): 1399-1411., articleTitle=A pericyte-glia scarring develops at the leaky capillaries in the hippocampus during seizure activity, refAbstract=null), Reference(id=1190669211530834250, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2017, volume=38, issue=3, pageStart=291, pageEnd=304, url=null, language=null, rfNumber=[39], rfOrder=38, authorNames=Rustenhoven J, Jansson D, Smyth LC, journalName=Trends Pharmacol Sci, refType=null, unstructuredReference=Rustenhoven J, Jansson D, Smyth LC, et al. Brain pericytes as mediators of neuroinflammation[J]. Trends Pharmacol Sci, 2017, 38(3): 291-304., articleTitle=Brain pericytes as mediators of neuroinflammation, refAbstract=null), Reference(id=1190669211602137420, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2018, volume=1692, issue=null, pageStart=34, pageEnd=44, url=null, language=null, rfNumber=[40], rfOrder=39, authorNames=Matsumoto J, Dohgu S, Takata F, journalName=Brain Res, refType=null, unstructuredReference=Matsumoto J, Dohgu S, Takata F, et al. TNF‑α‑sensitive brain pericytes activate microglia by releasing IL-6 through cooperation between IκB-NFκB and JAK-STAT3 pathways[J]. Brain Res, 2018, 1692: 34-44., articleTitle=TNF‑α‑sensitive brain pericytes activate microglia by releasing IL-6 through cooperation between IκB-NFκB and JAK-STAT3 pathways, refAbstract=null), Reference(id=1190669211732160845, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2018, volume=113, issue=null, pageStart=70, pageEnd=81, url=null, language=null, rfNumber=[41], rfOrder=40, authorNames=Klement W, Garbelli R, Zub E, journalName=Neurobiol Dis, refType=null, unstructuredReference=Klement W, Garbelli R, Zub E, et al. Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature[J]. Neurobiol Dis, 2018, 113: 70-81., articleTitle=Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature, refAbstract=null), Reference(id=1190669211841212750, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2011, volume=7, issue=1, pageStart=31, pageEnd=40, url=null, language=null, rfNumber=[42], rfOrder=41, authorNames=Vezzani A, French J, Bartfai T, journalName=Nat Rev Neurol, refType=null, unstructuredReference=Vezzani A, French J, Bartfai T, et al. The role of inflammation in epilepsy[J]. Nat Rev Neurol, 2011, 7(1): 31-40., articleTitle=The role of inflammation in epilepsy, refAbstract=null), Reference(id=1190669212034150735, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2023, volume=48, issue=8, pageStart=887, pageEnd=892, url=null, language=null, rfNumber=[43], rfOrder=42, authorNames=王大永, 裴剑, 洪铭岩, journalName=解放军医学杂志, refType=null, unstructuredReference=王大永, 裴剑, 洪铭岩, 等. 卡马西平对癫痫大鼠中脑腹侧被盖区多巴胺能神经元Kv7.4通道的影响[J]. 解放军医学杂志, 2023, 48(8): 887-892., articleTitle=卡马西平对癫痫大鼠中脑腹侧被盖区多巴胺能神经元Kv7.4通道的影响, refAbstract=null), Reference(id=1190669212130619728, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669166370762988, doi=null, pmid=null, pmcid=null, year=2019, volume=101, issue=null, pageStart=106285, pageEnd=null, url=null, language=null, rfNumber=[44], rfOrder=43, authorNames=Swissa E, Serlin Y, Vazana U, journalName=Epilepsy Behav, refType=null, unstructuredReference=Swissa E, Serlin Y, Vazana U, et al. Blood-brain barrier dysfunction in status epileptics: Mechanisms and role in epileptogenesis[J]. 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