Article(id=1190669165867446504, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1190669163988398295, articleNumber=null, orderNo=null, doi=10.11855/j.issn.0577-7402.0115.2024.0929, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=research-article, receivedDate=1706112000000, receivedDateStr=2024-01-25, revisedDate=null, revisedDateStr=null, acceptedDate=1711036800000, acceptedDateStr=2024-03-22, onlineDate=1761807250705, onlineDateStr=2025-10-30, pubDate=1745769600000, pubDateStr=2025-04-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1761807250705, onlineIssueDateStr=2025-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1761807250705, creator=13701087609, updateTime=1761807250705, updator=13701087609, issue=Issue{id=1190669163988398295, tenantId=1146029695717560320, journalId=1189873630562394117, year='2025', volume='50', issue='4', pageStart='367', pageEnd='503', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1761807250258, creator=13701087609, updateTime=1761807667423, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1190670913772339410, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1190669163988398295, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1190670913772339411, tenantId=1146029695717560320, journalId=1189873630562394117, issueId=1190669163988398295, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=418, endPage=426, ext={EN=ArticleExt(id=1190669166098133226, articleId=1190669165867446504, tenantId=1146029695717560320, journalId=1189873630562394117, language=EN, title=Predictive value of albumin, hemoglobin, and multifactorial model for poor postoperative prognosis in elderly patients with meningiomas, columnId=1190310109000602400, journalTitle=Medical Journal of Chinese People’s Liberation Army, columnName=Clinical Research, runingTitle=null, highlight=null, articleAbstract=
Objective To explore the predictive value of albumin, hemoglobin and multifactorial model for poor postoperative prognosis in elderly patients with meningioma. Methods A retrospective analysis was conducted on 253 elderly patients who underwent meningioma surgery and were transferred to the neurosurgical intensive care unit (NICU) at General Hospital of Northern Theater Command from January 2019 to September 2021, serving as the modeling cohort. Another 227 elderly patients who were treated in NICU after meningioma surgery from November 2021 to June 2023 were used as the validation cohort. Patients in the modeling cohort were categorized into good prognosis group [Glasgow Coma Scale (GCS) score>7, n=161] and poor prognosis group (GCS≤7, n=92) based on the GCS. Univariate and multifactorial logistic regression analyses were performed on the modeling cohort to identify independent risk factors, and a multifactorial model for predicting poor postoperative prognosis in elderly patients with meningioma was constructed based on these factors. The predictive efficacy and accuracy of the model were evaluated using the area under the receiver operating characteristic (ROC) curve (AUC), sensitivity, specificity, Hosmer-Lemeshow goodness-of-fit test, and calibration curves. The predictive value of postoperative albumin, hemoglobin, and the multifactorial models for postoperative prognosis in elderly meningioma patients was assessed using restricted cubic spline modeling (RCS), decision curves (DCA), and validated using an external validation cohort to assess the stability of the model. Results Meningioma WHO grade Ⅱ and Ⅲ (OR=3.994, 95%CI 1.963-8.126), postoperative hypoalbuminemia (OR=2.194, 95%CI 1.079-4.462), and postoperative anemia (OR=2.117, 95%CI 1.096-4.089) were identified as independent risk factors for poor postoperative prognosis in elderly meningioma patients (P<0.05), while the use of analgesic/sedative medications was a protective factor (OR=0.388, 95%CI 0.201-0.748, P<0.05). The Hosmer-Lemeshow test indicated that the constructed multifactorial model had a good fit accuracy (P=0.161). The AUC for predicting poor postoperative prognosis in elderly meningioma patients for postoperative albumin and hemoglobin were 0.545 (95%CI 0.472-0.617) and 0.632 (95%CI 0.561-0.702), respectively, and showed a nonlinear dose-response relationship with prognosis (P<0.01). DCA analysis results showed that the net benefit rate of multifactorial model was higher than that of postoperative albumin and hemoglobin when the threshold probabilities were between 0.10 and 0.90. The AUC for predicting postoperative prognosis in the elderly meningioma patients in the modeling and validation cohorts were 0.810 and 0.819, respectively, and their calibration curves suggested good discrimination and accuracy. Conclusions Meningioma WHO grades Ⅱ and Ⅲ, postoperative anemia and hypoalbuminemia are independent risk factors for poor postoperative prognosis in elderly meningioma patients, while the use of analgesic/sedative drugs is a protective factor. The multifactorial model constructed based on these factors has a good predictive efficacy and credibility, and can be used as a reference for clinical decision-making.
, correspAuthors=Hong Qu, authorNote=null, correspAuthorsNote=
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目的 探讨白蛋白、血红蛋白及多因素模型对老年脑膜瘤患者术后预后不良的预测价值。方法 回顾性纳入北部战区总医院2019年1月-2021年9月收治的253例老年脑膜瘤术后转入神经外科重症监护病房(NICU)治疗的患者作为建模集,2021年11月-2023年6月收治的227例老年脑膜瘤术后转入NICU治疗的患者作为验证集。根据格拉斯哥昏迷评分(GCS)将建模集患者分为预后良好组(GCS评分>7分,n=161)与预后不良组(GCS评分≤7分,n=92)。使用建模集进行单因素和多因素logistic回归分析以确定独立危险因素,并据此构建预测老年脑膜瘤患者术后预后不良的多因素模型。通过受试者操作特征(ROC)曲线下面积(AUC)、敏感度、特异度、Hosmer-Lemeshow拟合优度检验以及校准曲线评价模型的预测效能和准确度。通过限制性立方样条模型(RCS)、决策曲线(DCA)评估术后白蛋白、血红蛋白及多因素模型对老年脑膜瘤患者术后预后的预测价值,使用验证集进行验证以评估模型的稳定性。结果 脑膜瘤WHO Ⅱ级和Ⅲ级(OR=3.994,95%CI 1.963~8.126)、术后低蛋白血症(OR=2.194,95%CI 1.079~4.462)、术后贫血(OR=2.117,95%CI 1.096~4.089)是老年脑膜瘤患者术后预后不良的独立危险因素(P<0.05),而使用镇痛/镇静药物是其保护因素(OR=0.388,95%CI 0.201~0.748,P<0.05)。Hosmer-Lemeshow检验显示,所构建的多因素模型拟合准确度良好(P=0.161)。术后白蛋白、血红蛋白预测老年脑膜瘤患者术后预后不良的AUC分别为0.545(95%CI 0.472~0.617)、0.632(95%CI 0.561~0.702),且与预后不良呈非线性剂量反应关系(P<0.01)。DCA分析结果显示,阈值概率为0.10~0.90时,多因素模型较术后白蛋白、血红蛋白的净获益率高。该模型在建模集和验证集中预测老年脑膜瘤患者术后预后的AUC分别为0.810和0.819,其校准曲线提示区分度、准确度较好。结论 脑膜瘤WHO Ⅱ级和Ⅲ级、术后贫血及低蛋白血症是老年脑膜瘤患者术后预后不良的独立危险因素,而使用镇痛/镇静药物为其保护因素;基于此构建的多因素模型具有良好的预测效能,可信度较高,可用于临床决策的参考。
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拱艳羽,硕士研究生,主要从事神经重症基础与临床方面的研究
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2Department of Neurosurgery, General Hospital of Northern Theater Command, Shenyang, Liaoning 110016, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1190669337385120406, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, authorId=1190669337208959635, language=CN, stringName=曲虹, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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180: e281-e287., articleTitle=Prognostic factors affecting postsurgical outcomes of adult patients with intracranial meningioma: a retrospective study, refAbstract=null)], funds=[Fund(id=1190669341654921928, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, awardId=2021JH2/10300116, language=EN, fundingSource=Science and Technology Plan of Liaoning Province(2021JH2/10300116), fundOrder=null, country=null), Fund(id=1190669341726225097, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, awardId=2021JH2/10300116, language=CN, fundingSource=辽宁省科技计划(2021JH2/10300116), fundOrder=null, country=null), Fund(id=1190669341789139658, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, awardId=2022JH2/101500037, language=EN, fundingSource=Science and Technology Plan of Liaoning Province(2022JH2/101500037), fundOrder=null, country=null), Fund(id=1190669341860442827, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, awardId=2022JH2/101500037, language=CN, fundingSource=辽宁省科技计划(2022JH2/101500037), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1190669335829033603, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, xref=1, ext=[AuthorCompanyExt(id=1190669335837422212, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, companyId=1190669335829033603, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
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1中国医科大学北部战区总医院研究生培养基地,辽宁沈阳 110016)]), AuthorCompany(id=1190669335929696902, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, xref=2, ext=[AuthorCompanyExt(id=1190669335942279815, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, companyId=1190669335929696902, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2Department of Neurosurgery, General Hospital of Northern Theater Command, Shenyang, Liaoning 110016, China), AuthorCompanyExt(id=1190669335946474120, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, companyId=1190669335929696902, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2北部战区总医院神经外科,辽宁沈阳 110016)])], figs=[ArticleFig(id=1190669339352249013, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=EN, label=Fig.1, caption=
ROC curves of postoperative albumin, hemoglobin (A) and multifactorial modeling (B) for predicting prognosis in elderly postoperative patients with meningiomas, figureFileSmall=FyLqEtzGMu5d2cMSKk5uMg==, figureFileBig=LgIyOiesaM9QQXGD3t2/Gg==, tableContent=null), ArticleFig(id=1190669339419357878, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=CN, label=图1, caption=
术后白蛋白、血红蛋白(A)与多因素模型(B)预测老年脑膜瘤患者术后预后不良的ROC曲线, figureFileSmall=FyLqEtzGMu5d2cMSKk5uMg==, figureFileBig=LgIyOiesaM9QQXGD3t2/Gg==, tableContent=null), ArticleFig(id=1190669339595518647, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=EN, label=Fig.2, caption=
Calibration curves for internal validation of modeling sets, figureFileSmall=U9OytUfRW+24ZmCKSfc0jw==, figureFileBig=QdieFBQTydRKdCTlXWdWdQ==, tableContent=null), ArticleFig(id=1190669339662627512, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=CN, label=图2, caption=
采用建模集对预测模型进行内部验证的校准曲线, figureFileSmall=U9OytUfRW+24ZmCKSfc0jw==, figureFileBig=QdieFBQTydRKdCTlXWdWdQ==, tableContent=null), ArticleFig(id=1190669339721347769, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=EN, label=Fig.3, caption=
Dose-response relationship between postoperative albumin (A), postoperative hemoglobin (B), and poor postoperative prognosis based on a restricted cubic spline model, figureFileSmall=dcoCzUQyjtUZ6zdb+2e3Nw==, figureFileBig=rvVeK4nlEjUr7RobasDihg==, tableContent=null), ArticleFig(id=1190669339784262330, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=CN, label=图3, caption=
基于RCS模型分析术后白蛋白(A)、术后血红蛋白(B)与术后预后不良的剂量反应关系, figureFileSmall=dcoCzUQyjtUZ6zdb+2e3Nw==, figureFileBig=rvVeK4nlEjUr7RobasDihg==, tableContent=null), ArticleFig(id=1190669339842982587, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=EN, label=Fig.4, caption=
Decision curves of postoperative albumin and hemoglobin levels and the multifactor model, figureFileSmall=DQPzn9o9iednc7VCuMReIg==, figureFileBig=pJdIiqactmbEJKiKIn4/aw==, tableContent=null), ArticleFig(id=1190669339893314236, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=CN, label=图4, caption=
术后白蛋白、血红蛋白水平与多因素模型的决策曲线, figureFileSmall=DQPzn9o9iednc7VCuMReIg==, figureFileBig=pJdIiqactmbEJKiKIn4/aw==, tableContent=null), ArticleFig(id=1190669339952034493, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=EN, label=Fig.5, caption=
ROC curve and calibration curve for validation set multifactorial model to predict prognosis of elderly postoperative patients with meningiomas, figureFileSmall=zbJ/sbZLUBoXlkv7RHzLOg==, figureFileBig=jtCVSFKpcn6mzV+5n9UPlA==, tableContent=null), ArticleFig(id=1190669340014949054, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=CN, label=图5, caption=
验证集中多因素模型预测老年脑膜瘤患者术后预后不良的ROC曲线(A)和校准曲线(B), figureFileSmall=zbJ/sbZLUBoXlkv7RHzLOg==, figureFileBig=jtCVSFKpcn6mzV+5n9UPlA==, tableContent=null), ArticleFig(id=1190669340090446527, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=EN, label=Tab.1, caption=
Unifactorial analysis of poor prognosis in elderly postoperative patients with meningiomas
, figureFileSmall=null, figureFileBig=null, tableContent=
| 因素 | 预后良好组 (n=161) | 预后不良组 (n=92) | χ2/t | P |
|---|
| 年龄(岁, $\bar{x}±s$) | 68.8±2.8 | 68.9±3.1 | 0.389 | 0.698 |
| 男[例(%)] | 43(26.7) | 41(44.6) | 8.418 | 0.004 |
| 低蛋白血症[例(%)] | 85(52.8) | 67(72.8) | 9.794 | 0.002 |
| 贫血[例(%)] | 45(28.0) | 51(55.4) | 18.782 | <0.0001 |
| NICU留置时间(d, $\bar{x}±s$) | 5.13±2.60 | 5.69±2.23 | 1.746 | 0.082 |
| 术后继发性癫痫[例(%)] | 8(5.0) | 11(12.0) | 4.115 | 0.042 |
| 肿瘤部位[例(%)] | | | 12.181 | 0.032 |
| 大脑凸面 | 62(38.5) | 33(35.9) | | |
| 鞍区 | 64(39.8) | 28(30.4) | | |
| 小脑 | 18(11.2) | 9(9.8) | | |
| 脑室 | 4(2.5) | 6(6.5) | | |
| 脑干 | 1(0.6) | 6(6.5) | | |
| 其他 | 12(7.5) | 10(10.9) | | |
| 肾损伤[例(%)] | 31(19.3) | 25(27.2) | 2.130 | 0.144 |
| 肝损伤[例(%)] | 60(37.3) | 42(45.7) | 1.711 | 0.191 |
| 超敏C反应蛋白升高[例(%)] | 82(50.9) | 66(71.7) | 10.440 | 0.001 |
| WHO分级[例(%)] | | | 39.066 | <0.0001 |
| Ⅰ级 | 140(87.0) | 47(51.1) | | |
| Ⅱ、Ⅲ级 | 21(13.0) | 45(48.9) | | |
| 切除程度[例(%)] | | | 13.676 | <0.0001 |
| 大体全切除 | 141(87.6) | 63(68.5) | | |
| 次全切除 | 20(12.4) | 29(31.5) | | |
| 使用镇痛/镇静药物[例(%)] | | | 5.390 | 0.020 |
| 否 | 50(31.1) | 42(45.7) | | |
| 是 | 111(68.9) | 50(54.3) | | |
| 吸烟史[例(%)] | 59(36.6) | 34(37.0) | 0.002 | 0.961 |
| 饮酒史[例(%)] | 56(34.8) | 34(37.0) | 0.121 | 0.728 |
| 高血压[例(%)] | 62(38.5) | 39(42.4) | 0.368 | 0.544 |
| 糖尿病[例(%)] | 26(16.1) | 13(14.1) | 0.183 | 0.669 |
| 冠心病[例(%)] | 15(9.3) | 12(13.0) | 0.853 | 0.356 |
| 使用激素[例(%)] | 43(26.7) | 27(29.3) | 0.204 | 0.652 |
| BMI[例(%)] | | | 5.251 | 0.154 |
| <18.5 kg/m2 | 7(4.3) | 2(2.2) | | |
| 18.5~23.9 kg/m2 | 69(42.9) | 35(38.0) | | |
| 24.0~27.9 kg/m2 | 63(39.1) | 48(52.2) | | |
), ArticleFig(id=1190669340216275648, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=CN, label=表1, caption=
老年脑膜瘤患者术后预后不良的单因素分析
, figureFileSmall=null, figureFileBig=null, tableContent=
| 因素 | 预后良好组 (n=161) | 预后不良组 (n=92) | χ2/t | P |
|---|
| 年龄(岁, $\bar{x}±s$) | 68.8±2.8 | 68.9±3.1 | 0.389 | 0.698 |
| 男[例(%)] | 43(26.7) | 41(44.6) | 8.418 | 0.004 |
| 低蛋白血症[例(%)] | 85(52.8) | 67(72.8) | 9.794 | 0.002 |
| 贫血[例(%)] | 45(28.0) | 51(55.4) | 18.782 | <0.0001 |
| NICU留置时间(d, $\bar{x}±s$) | 5.13±2.60 | 5.69±2.23 | 1.746 | 0.082 |
| 术后继发性癫痫[例(%)] | 8(5.0) | 11(12.0) | 4.115 | 0.042 |
| 肿瘤部位[例(%)] | | | 12.181 | 0.032 |
| 大脑凸面 | 62(38.5) | 33(35.9) | | |
| 鞍区 | 64(39.8) | 28(30.4) | | |
| 小脑 | 18(11.2) | 9(9.8) | | |
| 脑室 | 4(2.5) | 6(6.5) | | |
| 脑干 | 1(0.6) | 6(6.5) | | |
| 其他 | 12(7.5) | 10(10.9) | | |
| 肾损伤[例(%)] | 31(19.3) | 25(27.2) | 2.130 | 0.144 |
| 肝损伤[例(%)] | 60(37.3) | 42(45.7) | 1.711 | 0.191 |
| 超敏C反应蛋白升高[例(%)] | 82(50.9) | 66(71.7) | 10.440 | 0.001 |
| WHO分级[例(%)] | | | 39.066 | <0.0001 |
| Ⅰ级 | 140(87.0) | 47(51.1) | | |
| Ⅱ、Ⅲ级 | 21(13.0) | 45(48.9) | | |
| 切除程度[例(%)] | | | 13.676 | <0.0001 |
| 大体全切除 | 141(87.6) | 63(68.5) | | |
| 次全切除 | 20(12.4) | 29(31.5) | | |
| 使用镇痛/镇静药物[例(%)] | | | 5.390 | 0.020 |
| 否 | 50(31.1) | 42(45.7) | | |
| 是 | 111(68.9) | 50(54.3) | | |
| 吸烟史[例(%)] | 59(36.6) | 34(37.0) | 0.002 | 0.961 |
| 饮酒史[例(%)] | 56(34.8) | 34(37.0) | 0.121 | 0.728 |
| 高血压[例(%)] | 62(38.5) | 39(42.4) | 0.368 | 0.544 |
| 糖尿病[例(%)] | 26(16.1) | 13(14.1) | 0.183 | 0.669 |
| 冠心病[例(%)] | 15(9.3) | 12(13.0) | 0.853 | 0.356 |
| 使用激素[例(%)] | 43(26.7) | 27(29.3) | 0.204 | 0.652 |
| BMI[例(%)] | | | 5.251 | 0.154 |
| <18.5 kg/m2 | 7(4.3) | 2(2.2) | | |
| 18.5~23.9 kg/m2 | 69(42.9) | 35(38.0) | | |
| 24.0~27.9 kg/m2 | 63(39.1) | 48(52.2) | | |
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Multifactor logistic regression analysis assignment table
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| 因素 | 赋值 |
|---|
| 性别 | 女=0,男=1 |
| 术后低蛋白血症 | 无=0,有=1 |
| 术后贫血 | 无=0,有=1 |
| 术后继发性癫痫 | 无=0,有=1 |
| 肿瘤部位 | 其他=0,大脑凸面=1,鞍区=2,小脑=3,脑室=4,脑干=5 |
| 超敏C反应蛋白升高 | 无=0,有1 |
| WHO分级 | Ⅰ级=0,Ⅱ级和Ⅲ级=1 |
| 肿瘤切除程度 | 次全切除=0,大体全切除=1 |
| 镇静/镇痛药物 | 不使用=0,使用=1 |
| 预后情况 | 良好=0,不良=1 |
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多因素logistic回归分析各变量赋值表
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| 因素 | 赋值 |
|---|
| 性别 | 女=0,男=1 |
| 术后低蛋白血症 | 无=0,有=1 |
| 术后贫血 | 无=0,有=1 |
| 术后继发性癫痫 | 无=0,有=1 |
| 肿瘤部位 | 其他=0,大脑凸面=1,鞍区=2,小脑=3,脑室=4,脑干=5 |
| 超敏C反应蛋白升高 | 无=0,有1 |
| WHO分级 | Ⅰ级=0,Ⅱ级和Ⅲ级=1 |
| 肿瘤切除程度 | 次全切除=0,大体全切除=1 |
| 镇静/镇痛药物 | 不使用=0,使用=1 |
| 预后情况 | 良好=0,不良=1 |
), ArticleFig(id=1190669340413407939, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=EN, label=Tab.3, caption=
Multifactorial logistic regression analysis of poor prognosis in elderly postoperative patients with meningiomas
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| 因素 | 偏回归系数 | 标准误 | Wald | P | OR | 95%CI |
|---|
| 术后低蛋白血症 | 0.786 | 0.362 | 4.704 | 0.030 | 2.194 | 1.079~4.462 |
| 术后贫血 | 0.750 | 0.336 | 4.989 | 0.026 | 2.117 | 1.096~4.089 |
| WHO分级(Ⅱ、Ⅲ级) | 1.385 | 0.362 | 14.597 | <0.0001 | 3.994 | 1.963~8.126 |
| 使用镇痛/镇静药物 | -0.947 | 0.335 | 8.002 | 0.005 | 0.388 | 0.201~0.748 |
| 常量 | -2.983 | 0.883 | 11.416 | 0.001 | 0.051 | - |
), ArticleFig(id=1190669340476322500, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=CN, label=表3, caption=
老年脑膜瘤患者术后预后不良的多因素logistic回归分析
, figureFileSmall=null, figureFileBig=null, tableContent=
| 因素 | 偏回归系数 | 标准误 | Wald | P | OR | 95%CI |
|---|
| 术后低蛋白血症 | 0.786 | 0.362 | 4.704 | 0.030 | 2.194 | 1.079~4.462 |
| 术后贫血 | 0.750 | 0.336 | 4.989 | 0.026 | 2.117 | 1.096~4.089 |
| WHO分级(Ⅱ、Ⅲ级) | 1.385 | 0.362 | 14.597 | <0.0001 | 3.994 | 1.963~8.126 |
| 使用镇痛/镇静药物 | -0.947 | 0.335 | 8.002 | 0.005 | 0.388 | 0.201~0.748 |
| 常量 | -2.983 | 0.883 | 11.416 | 0.001 | 0.051 | - |
), ArticleFig(id=1190669340568597189, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=EN, label=Tab.4, caption=
Comparison of independent predictors and the predictive effect of multifactorial models in elderly patients with postoperative meningiomas
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| 指标 | AUC | 95%CI | 最佳截断值 | 敏感度(%) | 特异度(%) | P |
|---|
| 多因素模型 | 0.810 | 0.754~0.867 | 0.553 | 86.3 | 66.3 | 0.001 |
| 术后血红蛋白 | 0.632 | 0.561~0.702 | 118.5 g/L | 59.6 | 63.0 | 0.001 |
| 术后白蛋白 | 0.545 | 0.472~0.617 | 35.1 g/L | 46.0 | 68.5 | 0.237 |
), ArticleFig(id=1190669341575230150, tenantId=1146029695717560320, journalId=1189873630562394117, articleId=1190669165867446504, language=CN, label=表4, caption=
老年脑膜瘤患者术后的独立预测指标及多因素模型的预测效果比较
, figureFileSmall=null, figureFileBig=null, tableContent=
| 指标 | AUC | 95%CI | 最佳截断值 | 敏感度(%) | 特异度(%) | P |
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| 多因素模型 | 0.810 | 0.754~0.867 | 0.553 | 86.3 | 66.3 | 0.001 |
| 术后血红蛋白 | 0.632 | 0.561~0.702 | 118.5 g/L | 59.6 | 63.0 | 0.001 |
| 术后白蛋白 | 0.545 | 0.472~0.617 | 35.1 g/L | 46.0 | 68.5 | 0.237 |
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