Journal of Animal Science and Biotechnology

Journal of Animal Science and Biotechnology ›› 2026, Vol. 17 ›› Issue (4) : 2256 - 2272. DOI: 10.1186/s40104-026-01417-8

ANIMAL NUTRITION AND FEEDSTUFF

Efficacy and safety evaluation of artificial intelligence-identified antimicrobial peptides targeting avian pathogenic Escherichia coli in broiler chickens

Emre Demirsoy ¹^,²^,³ ,
Teagan I. Parkin ⁴ ,
Shaeleen E. Mihalynuk ⁴ ,
Anna H. Dema ⁴ ,
Lorissa Corrie ⁴ ,
Marika E. Heilker ⁴ ,
Haley N. Kuecks-Winger ⁴ ,
Anat Yanai ⁵^,⁶ ,
Uluc B. Birol ⁶ ,
Michael Mcllwee ⁷ ,
Kay de Wet ⁷ ,
Mathijs Knipscheer ⁷ ,
Victoria Bowes ⁷ ,
Vanessa Tuytel ⁷ ,
Liam Ritchie ⁷ ,
Wolfgang Köster ⁸ ,
Emil Berberov ⁸ ,
William R. Cox ⁶ ,
Monica Kotkoff ⁵ ,
Vanessa C. Thompson ⁴ ,
René L. Warren ¹ ,
Erin Fraser ⁹^,¹⁰ ,
Linda M. N. Hoang ²^,¹¹ ,
Fraser Hof ¹² ,
Fatih Birol ⁶ ,
Caren C. Helbing ⁴ ,
Inanc Birol ²^,³^,⁵^,⁶^,¹³^,^*

Author information +

¹BC Cancer, Vancouver, BC V5Z 1L3, Canada

²British Columbia Centre for Disease Control, Public Health Laboratory, Vancouver, BC V6Z R4R, Canada

³Genome Science and Technology Graduate Program, University of British Columbia, Vancouver, BC V6T 1Z4, Canada

⁴Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC V8P 5C2, Canada

⁵Canada's Michael Smith Genome Sciences Centre at BC Cancer, Vancouver, BC V5Z 4S6, Canada

⁶Amphoraxe Life Sciences Inc., Vancouver, BC V6L 3C9, Canada

⁷SJ Ritchie Research Farms, Abbotsford, BC V4X 2N4, Canada

⁸Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, Saskatoon, SK S7N 5E3, Canada

⁹Communicable Disease Prevention and Response, British Columbia Centre for Disease Control, Vancouver, BC V6Z R4R, Canada

¹⁰School of Population and Public Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada

¹¹Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, Canada

¹²Department of Chemistry, University of Victoria, Victoria, BC V8P 5C2, Canada

¹³Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada

^* Inanc Birol inanc.birol@ubc.ca

收起

Received	Accepted	Published
2025-11-08	2026-04-09
Issue Date
2026-08-13

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