Transient electromagnetic method (TEM) is an effective method for deep-sea polymetallic sulfide exploration. High-grade metal components in seafloor polymetallic sulfides cause extremely strong induced polarization effects and have a significant impact on transient electromagnetic response. In this paper, the inductive effects of deep-sea polymetallic sulfides were analyzed through laboratory measurement and numerical simulation. First, systematic electrical tests were carried out on rock ore samples from the hydrothermal vent fields on the southwest Indian Ocean Ridge. The complex resistivity of typical sulfides has a phase shift of up to 160 mrad in the frequency domain. The time domain and frequency domain measurements show that the polarizability parameter is a good indicator to distinguish sulfide minerals and surrounding rocks. Using the Cole-Cole model to interpret the complex resistivity to obtain the characteristic parameters of complex resistivity, the relationship between parameters and the composition and structure of the massive sulfide was analyzed, and the typical sulfides were classified based on the polarizability parameter. The induced polarization parameters of the typical sulfides were used to calculate the transient electromagnetic response of the layered medium, which show that the influence of induced polarization effect can be observed simultaneously in the best observation window of the TEM response of the deep-sea polymetallic sulfide deposit. Although the transient response is distorted in the late stage of the acquisition window, in the early stage of signal reception, the induced polarization effect effectively enhances the detection capability of the TEM for deep-sea polymetallic sulfides, which provides an explanation basis for the transient electromagnetic measurement data.