Based on the observation data from 163 GPS continuous stations in Qinghai-Xizang plateau and adjacent areas from 2010 to 2020, we solve the GPS vertical coordinate time series. Using the global loading grid data provided by GFZ, the environmental loading displacements are calculated by double cubic linear interpolation method, and the GPS vertical time series are corrected. The results show that the hydrological loading has the greatest influence on GPS station displacement in the study area, which is larger in the southern stations, with a RMS of 9.45 mm(MUET site). By comparing the changes of weighted root mean square(WRMS), annual term amplitude and velocity uncertainty before and after environmental loading correction, it is found that the environmental loading correction is able to weaken the nonlinear variations of vertical time series of most GPS stations in Qinghai-Xizang plateau and adjacent areas and it can accurately improve the velocity accuracy of most GPS stations.