Developing potent anti-inflammatory IRAK4-targeting PROTACs with simplified CRBN ligands
aKey Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China
bState Key Laboratory of Molecular Oncology, MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Tsinghua University, Beijing 100084, China
cChangping Laboratory, Beijing 102206, China
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