Batch and continuous-flow asymmetric synthesis of D-pantothenic acid precursor enabled by immobilized ketoreductase mutant
aDepartment of Chemistry, Engineering Center of Catalysis and Synthesis for Chiral Molecules, State Key Laboratory of Green Chemical Synthesis and Conversion, Fudan University, Shanghai 200433, China
bKey Laboratory of Green Chemical Engineering Process of Ministry of Education, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan 430205, China
cShanghai Engineering Research Center of Industrial Asymmetric Catalysis of Chiral Drugs, Shanghai 200433, China
dInstitute of Flow Chemistry and Engineering, College of Chemistry and Materials, Jiangxi Normal University, Nanchang 330022, China
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Department of Chemistry, Engineering Center of Catalysis and Synthesis for Chiral Molecules, State Key Laboratory of Green Chemical Synthesis and Conversion, Fudan University, Shanghai 200433, China.
zhangyajiao@fudan.edu.cn (Y. Zhang)
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