Rational structure-based design and optimization of next-generation biphenyl-piperidine-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors
aInstitute of Pharmaceutical Research and School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China
bState Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China
cDepartment of Chemistry, Engineering Center of Catalysis and Synthesis for Chiral Molecules, Fudan University, Shanghai 200433, China
dShanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China
eLaboratory of Virology and Chemotherapy, Rega Institute for Medical Research, KU Leuven, Leuven B-3000, Belgium
fDepartment of Life and Environmental Sciences, University of Cagliari, Monserrato I-09042, Italy
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