Bioassay- and molecular network-guided discovery of PPAP derivatives from Hypericum monogynum with inhibitory activity against cardiac valve calcification
aDepartment of Cardiology, Heart Center of Henan Provincial People’s Hospital, Central China Fuwai Hospital, Central China Fuwai Hospital of Zhengzhou University, Zhengzhou 450003, China
bHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
cLaboratory of Clinical Research Center, Department of Pathology, Heping Hospital Affiliated to Changzhi Medical College, Changzhi 046000, China
dShanxi Provincial Department-Municipal Key Laboratory Cultivation Base for Quality Enhancement and Utilization of Shang Dang Chinese Medicinal Materials, School of Pharmacy, Changzhi Medical College, Changzhi 046000, China
eHubei Shizhen Laboratory, Wuhan 430061, China
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