^a Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410083, China

^b National Engineering Research Center of Rice and Byproduct Deep Processing, School of Food Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, China

^c State Key Laboratory of Drug Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

^d Department of Geriatrics, Third Xiangya Hospital, Central South University, Changsha 410013, China