^aSchool of Traditional Chinese Materia Medica, Key Laboratory of Innovative Traditional Chinese Medicine for Major Chronic Diseases of Liaoning province, Key Laboratory for TCM Material Basis Study and Innovative Drug Development of Shenyang City, Shenyang Pharmaceutical University, Shenyang 110016, China

^bKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Key Laboratory of Research and Development for Natural Products; School of Pharmacy and School of Chemical Science and Technology, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming 650091, China

^cSchool of Pharmacy, Nantong University, Nantong 226001, China

^dSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China

^eState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China

^fCollege of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China

^gFaculty of Pharmaceutical Sciences, Toho University, Funabashi, Chiba 274-8510, Japan

^hSchool of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China