^a State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

^b Shandong Laboratory of Yantai Drug Discovery, Bohai rim Advanced Research Institute for Drug Discovery, Yantai 264117, China

^c Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095, United States

^d Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals and College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China

^e Key Laboratory for Carbonaceous Waste Processing and Process Intensification Research of Zhejiang Province, Department of Chemical and Environmental Engineering, The University of Nottingham Ningbo China, Ningbo 315100, China

^f School of Medicine, Shanghai University, Shanghai 200444, China

^g University of Chinese Academy of Sciences, Beijing 100049, China