The industry is the pillar industry of national economy. In the process of industrial production, its virtual simulation is carried out with the computer simulation technology, the running conditions of production line could be simulated by the simulation technology so that the rhythm of production and technological process are optimized as well as production efficiency and capacity are improved; the layout of production line, process arrangement and equipment configuration are optimized to improve production efficiency, reduce production costs and waste of resources. In the paper, the solutions for intelligent production line of rare earth oxides are designed with the computer virtual simulation technology by taking the intelligent manufacturing project for production line of rare earth products as example. It plays role in optimizing the technological process of intelligent manufacturing and layout of production line of rare earth oxides products. Moreover, the real scenarios of industrial production and virtual reality simulation are deeply integrated with the simulation technology so that customers could truly feel and understand the intelligent manufacturing process of production line of rare earth oxides.