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Dental caries represents a significant global health challenge. Accurate quantification of the mechanical properties of dental tissues is essential for understanding disease progression and guiding medical procedures. However, comprehensive comparative analyses across multiple stages of natural caries progression using a unified methodological framework remain limited. This study employs a multimodal approach, integrating several experimental techniques to evaluate the preliminary trends in microstructure and mechanical behaviour of human enamel and dentine affected by white spot lesion in the vicinity of the fissure apex, non-cavitated, and cavitated brown spot lesions. The preliminary results suggest that certain pathological alterations, specifically within the examined brown spot lesions-affected tissues, may display enhanced mechanical properties, which could be attributed to subsurface remineralisation and mineral deposition in sclerotic dentine. In contrast, advanced lesions, particularly those with structural breakdown, appear to exhibit significant reductions in mechanical properties, reflecting extensive demineralisation within the studied specimens. Furthermore, the fissure region was found to be particularly susceptible to mechanical degradation, with localised pathologically altered area seemingly influenced by morphological factors. These initial findings highlight the critical role of microstructural features in modulating the biomechanical response of dental tissues to pathological challenges and provide a basis for broader statistical validation.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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