Home Journals Articles Updates About
CN
image
收藏切换
Electrostatically Assembled HA-DN/AMSN-TCS Coatings for Antibacterial Urinary Catheters
收藏切换
PDF
Jiafeng Hu1, 2, Xiaojun Chen1, 2, Yingwei Chen3, Lin Wu1, 2, Chengxiong Lin1, 2
Biosurface and Biotribology | 2026, 12(1) : e70022
Less
收藏切换
Biosurface and Biotribology | 2026, 12(1): e70022
• ORIGINAL RESEARCH •
Electrostatically Assembled HA-DN/AMSN-TCS Coatings for Antibacterial Urinary Catheters
Full
Jiafeng Hu1, 2, Xiaojun Chen1, 2, Yingwei Chen3, Lin Wu1, 2, Chengxiong Lin1, 2
Affiliations
  • 1Key Laboratory of Metallurgical Equipment and Control Technology, Ministry of Education, Wuhan University of Science and Technology, Wuhan, China
  • 2Hubei Key Laboratory of Mechanical Transmission and Manufacturing Engineering, Wuhan University of Science and Technology, Wuhan, China
  • 3School of Mathematics and Computer Science, Wuhan Polytechnic University, Wuhan, China
doi: 10.1049/bsb2.70022
Outline
收藏切换

Catheter-associated urinary tract infections (CAUTIs) are a significant complication of indwelling urinary catheters, primarily caused by bacterial adhesion, biofilm formation and catheter-induced mechanical irritation. To reduce the risk of infection and enhance catheter safety and performance, this study developed an antibacterial lubricating coating. The coating was fabricated on a polytetrafluoroethylene (PTFE) substrate via electrostatic self-assembly, combining dopamine-modified hyaluronic acid-dopamine (HA-DN) as a biomimetic adhesive with aminated mesoporous silica nanoparticles (AMSN) serving as a long-acting drug delivery carrier loaded with triclosan (TCS). The results demonstrated that the prepared AMSN exhibited a uniform particle size of approximately 80 nm, an ordered mesoporous structure and a high drug-loading capacity, enabling sustained in vitro release of TCS for up to 144 h. Additionally, the composite multilayer coating significantly improved surface hydrophilicity and lubricity, exhibited strong antibacterial activity against Escherichia coli and Staphylococcus aureus and maintained good biocompatibility. These findings highlight its potential for preventing CAUTIs and enhancing the safety of indwelling urinary catheters.

adhesion and friction  /  antifungi  /  antimicrobial  /  biointerface  /  biological adhesion
Jiafeng Hu, Xiaojun Chen, Yingwei Chen, Lin Wu, Chengxiong Lin. Electrostatically Assembled HA-DN/AMSN-TCS Coatings for Antibacterial Urinary Catheters[J]. Biosurface and Biotribology, 2026 , 12 (1) : e70022 - . DOI: 10.1049/bsb2.70022
Full Text
Less
Funding
Less
  • National Natural Science Foundation of China(52205186)
Appendix
Less
Year 2026 volume 12 Issue 1
PDF
29
7
Cite this Article
BibTeX
Article Info
doi: 10.1049/bsb2.70022
  • Receive Date：2025-12-29
  • Online Date：2026-08-27
Article Data
Affiliations
History
  • Received：2025-12-29
  • Revised：2026-04-14
  • Accepted：2026-04-21
Funding
National Natural Science Foundation of China(52205186)
Affiliations
    1Key Laboratory of Metallurgical Equipment and Control Technology, Ministry of Education, Wuhan University of Science and Technology, Wuhan, China
    2Hubei Key Laboratory of Mechanical Transmission and Manufacturing Engineering, Wuhan University of Science and Technology, Wuhan, China
    3School of Mathematics and Computer Science, Wuhan Polytechnic University, Wuhan, China

Corresponding:

Lin Wu ()
Chengxiong Lin ()
References
Share
https://castjournals.cast.org.cn/joweb/bab/EN/10.1049/bsb2.70022
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House