Acta Pharmaceutica Sinica B

Acta Pharmaceutica Sinica B ›› 2025, Vol. 15 ›› Issue (3) : 1447 - 1462. DOI: 10.1016/j.apsb.2024.12.028

ORIGINAL ARTICLE

A synthetic peptide, derived from neurotoxin GsMTx4, acts as a non-opioid analgesic to alleviate mechanical and neuropathic pain through the TRPV4 channel

ShaoXi Ke ^a^,^b ,
Ping Dong ^a^,^c ,
Yi Mei ^a ,
JiaQi Wang ^a ,
Mingxi Tang ^d^,^e ,
Wanxin Su ^a ,
JingJing Wang ^a ,
Chen Chen ^a ,
Xiaohui Wang ^a ,
JunWei Ji ^a ,
XinRan Zhuang ^a ,
ShuangShuang Yang ^a ,
Yun Zhang ^a ,
Linda M. Boland ^f ,
Meng Cui ^g ,
Masahiro Sokabe ^h^,ⁱ ,
Zhe Zhang ^a^,^j^,^* ,
QiongYao Tang ^a^,^j^,^*

Author information +

^aJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou 221004, China

^bThe Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310007, China

^cRuijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 201801, China

^dDepartment of Pathology, Yaan People's Hospital (Yaan Hospital of West China Hospital of Sichuan University), Ya'an 625000, China

^eDepartment of Pathology, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China

^fDepartment of Biology, University of Richmond, Richmond, VA 23173, USA

^gDepartment of Pharmaceutical Sciences, Northeastern University School of Pharmacy, Boston, MA 02115, USA

^hMechanobiology Laboratory, Nagoya University, Graduate School of Medicine, Nagoya 464-8601, Japan

ⁱHuman Information Systems Lab, Kanazawa Institute of Technology, Kanazawa 921-8501, Japan

^jNMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Xuzhou Medical University, Xuzhou 221004, China

^* Corresponding authors.

收起

Received	Accepted	Published
2024-07-23	2024-11-14
Issue Date
2026-09-18

Accesses

Total: 10

	Just accepted	Online first	Issue	Totals
HTML pages views	0	0	6	6
PDF downloads	0	0	4	4

Accesses in the last 12 months

Accesses come from

Citations

Citation counts are provided from Web of Science and CrossRef. The counts may vary by service, and are reliant on the availability of their data. Counts will update daily once available.

Search

Online attention

The hierarchy quorum sensing network in Pseudomonas aeruginosa

Full Text HTML

PDF (887KB)

Recommended